Kinderen met obesitas en afbuigende lengtegroeicurve: ziekte van Cushing?

Esther M van Wezel; Hanneke M van Santen; Wouter R van Furth; Liesbeth Reneman; Peter H Bisschop; A S Paul van Trotsenburg

Kinderen met obesitas en afbuigende lengtegroeicurve: ziekte van Cushing?

Translated title of the contribution: Children with obesity and declining linear growth curve: Cushing's disease?

Esther M van Wezel
, Hanneke M van Santen
, Wouter R van Furth
, Liesbeth Reneman
, Peter H Bisschop
, A S Paul van Trotsenburg

Child Health

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We describe two children who presented with extreme weight gain and failure to grow in height, and who were both diagnosed with Cushing's disease. Following preoperative metyrapone treatment, both children successfully underwent curative transsphenoidal surgery. While obesity is a common and increasing problem in childhood, Cushing's disease is rare. The combination of weight gain and growth failure in a child is an alarming sign in which underlying endocrine disease must be ruled out.

Translated title of the contribution	Children with obesity and declining linear growth curve: Cushing's disease?
Original language	Dutch
Pages (from-to)	A4677
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	156
Issue number	51
Publication status	Published - 2012

Keywords

Adenoma
Body Height
Child
Cushing Syndrome
Dexamethasone
Diagnosis, Differential
Female
Humans
Obesity
Pituitary Neoplasms
Treatment Outcome
Case Reports
English Abstract
Journal Article

Cite this

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title = "Kinderen met obesitas en afbuigende lengtegroeicurve: ziekte van Cushing?",

abstract = "We describe two children who presented with extreme weight gain and failure to grow in height, and who were both diagnosed with Cushing's disease. Following preoperative metyrapone treatment, both children successfully underwent curative transsphenoidal surgery. While obesity is a common and increasing problem in childhood, Cushing's disease is rare. The combination of weight gain and growth failure in a child is an alarming sign in which underlying endocrine disease must be ruled out.",

keywords = "Adenoma, Body Height, Child, Cushing Syndrome, Dexamethasone, Diagnosis, Differential, Female, Humans, Obesity, Pituitary Neoplasms, Treatment Outcome, Case Reports, English Abstract, Journal Article",

author = "\{van Wezel\}, \{Esther M\} and \{van Santen\}, \{Hanneke M\} and \{van Furth\}, \{Wouter R\} and Liesbeth Reneman and Bisschop, \{Peter H\} and \{van Trotsenburg\}, \{A S Paul\}",

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language = "Dutch",

volume = "156",

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journal = "Nederlands Tijdschrift voor Geneeskunde",

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T1 - Kinderen met obesitas en afbuigende lengtegroeicurve

T2 - ziekte van Cushing?

AU - van Wezel, Esther M

AU - van Santen, Hanneke M

AU - van Furth, Wouter R

AU - Reneman, Liesbeth

AU - Bisschop, Peter H

AU - van Trotsenburg, A S Paul

PY - 2012

Y1 - 2012

N2 - We describe two children who presented with extreme weight gain and failure to grow in height, and who were both diagnosed with Cushing's disease. Following preoperative metyrapone treatment, both children successfully underwent curative transsphenoidal surgery. While obesity is a common and increasing problem in childhood, Cushing's disease is rare. The combination of weight gain and growth failure in a child is an alarming sign in which underlying endocrine disease must be ruled out.

AB - We describe two children who presented with extreme weight gain and failure to grow in height, and who were both diagnosed with Cushing's disease. Following preoperative metyrapone treatment, both children successfully underwent curative transsphenoidal surgery. While obesity is a common and increasing problem in childhood, Cushing's disease is rare. The combination of weight gain and growth failure in a child is an alarming sign in which underlying endocrine disease must be ruled out.

KW - Adenoma

KW - Body Height

KW - Child

KW - Cushing Syndrome

KW - Dexamethasone

KW - Diagnosis, Differential

KW - Female

KW - Humans

KW - Obesity

KW - Pituitary Neoplasms

KW - Treatment Outcome

KW - Case Reports

KW - English Abstract

KW - Journal Article

M3 - Article

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SP - A4677

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

IS - 51

ER -

Kinderen met obesitas en afbuigende lengtegroeicurve: ziekte van Cushing?

Abstract

Keywords

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