Abstract
In vitro fertilisation (IVF) usually involves controlled ovarian stimulation (COS). There is now increasing emphasis on methods that make IVF safer and more patient-friendly. Modified natural cycle (MNC)-IVF is an example of this. In MNC-IVF spontaneous ovulation is prevented with a minimal amount of hormones and spontaneous monofollicular growth is supported. As a result, there is no risk of ovarian hyperstimulation syndrome, and the risk of a multiple pregnancy is low. There is a 9.1% chance of a pregnancy after one MNC-cycle and the cumulative pregnancy rate after a maximum of 6 MNC-IVF cycles is 33.4%. The cumulative results of a maximum of 6 MNC-IVF cycles are comparable to those of the first COS-IVF treatment cycle including transfer of cryopreserved embryos produced as a result of the treatment (33.4% versus 37.7%). The risk of a twin pregnancy following MNC-IVF is 0.1%, and 18.3% following COS-IVF. This means that MNC-IVF is a good alternative for COS-IVF.
| Translated title of the contribution | IVF in a modified natural cycle |
|---|---|
| Original language | Dutch |
| Pages (from-to) | A2519 |
| Journal | Nederlands Tijdschrift voor Geneeskunde |
| Volume | 154 |
| Issue number | 45 |
| Publication status | Published - 2010 |
| Externally published | Yes |
Keywords
- Female
- Fertilization in Vitro/methods
- Follicle Stimulating Hormone, Human/therapeutic use
- Humans
- Infertility, Female/therapy
- Ovarian Hyperstimulation Syndrome/prevention & control
- Ovulation Induction/methods
- Pregnancy
- Pregnancy Rate
- Pregnancy, Multiple