Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease

T. A. De Heer-Groen; A. B.J. Prakken; N. M.A. Bax; P. J. Van Dijken

doi:10.1007/s004310050524

Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease

T. A. De Heer-Groen, A. B.J. Prakken, N. M.A. Bax^*, P. J. Van Dijken

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely. Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.

Original language	English
Pages (from-to)	1015-1017
Number of pages	3
Journal	European Journal of Pediatrics
Volume	155
Issue number	12
DOIs	https://doi.org/10.1007/s004310050524
Publication status	Published - 30 Nov 1996

Keywords

Castleman disease
Childhood
Microcytic anaemia

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title = "Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease",

abstract = "We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely. Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.",

keywords = "Castleman disease, Childhood, Microcytic anaemia",

author = "{De Heer-Groen}, {T. A.} and Prakken, {A. B.J.} and Bax, {N. M.A.} and {Van Dijken}, {P. J.}",

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AU - De Heer-Groen, T. A.

AU - Prakken, A. B.J.

AU - Bax, N. M.A.

AU - Van Dijken, P. J.

PY - 1996/11/30

Y1 - 1996/11/30

N2 - We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely. Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.

AB - We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely. Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.

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KW - Childhood

KW - Microcytic anaemia

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JO - European Journal of Pediatrics

JF - European Journal of Pediatrics

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ER -

Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease

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