Inulin measurement in serum and urine with an autoanalyser, corrected for glucose interference

E. G.W. Lentjes; K. W. Florijn; P. C. Chang; W. Van Dam

Inulin measurement in serum and urine with an autoanalyser, corrected for glucose interference

E. G.W. Lentjes, K. W. Florijn, P. C. Chang, W. Van Dam

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Abstract

A method is described for the semi-automated measurement of inulin concentrations in serum and urine in the presence of glucose. The concentration of glucose is measured simultaneously and is used to correct for almost all 'inulin-like' interferences. The inulin standard curve is linear over a wide range (5-2500 mg/l). Between-run precision is < 6% and recovery from spiked sera is 98%. This method offers the possibility of measuring glomerular filtration rate in patients with varying glucose concentrations (e.g. diabetics).

Original language	English
Pages (from-to)	625-628
Number of pages	4
Journal	European journal of clinical chemistry and clinical biochemistry
Volume	32
Issue number	8
Publication status	Published - 1 Jan 1994

Cite this

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abstract = "A method is described for the semi-automated measurement of inulin concentrations in serum and urine in the presence of glucose. The concentration of glucose is measured simultaneously and is used to correct for almost all 'inulin-like' interferences. The inulin standard curve is linear over a wide range (5-2500 mg/l). Between-run precision is < 6\% and recovery from spiked sera is 98\%. This method offers the possibility of measuring glomerular filtration rate in patients with varying glucose concentrations (e.g. diabetics).",

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AU - Chang, P. C.

AU - Van Dam, W.

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N2 - A method is described for the semi-automated measurement of inulin concentrations in serum and urine in the presence of glucose. The concentration of glucose is measured simultaneously and is used to correct for almost all 'inulin-like' interferences. The inulin standard curve is linear over a wide range (5-2500 mg/l). Between-run precision is < 6% and recovery from spiked sera is 98%. This method offers the possibility of measuring glomerular filtration rate in patients with varying glucose concentrations (e.g. diabetics).

AB - A method is described for the semi-automated measurement of inulin concentrations in serum and urine in the presence of glucose. The concentration of glucose is measured simultaneously and is used to correct for almost all 'inulin-like' interferences. The inulin standard curve is linear over a wide range (5-2500 mg/l). Between-run precision is < 6% and recovery from spiked sera is 98%. This method offers the possibility of measuring glomerular filtration rate in patients with varying glucose concentrations (e.g. diabetics).

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SN - 0939-4974

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JF - European journal of clinical chemistry and clinical biochemistry

IS - 8

ER -

Inulin measurement in serum and urine with an autoanalyser, corrected for glucose interference

Abstract

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