Intravenous lipid emulsions as an antidote in the veterinary practice Part 2: Practical guidelines

Marieke A. Dijkman*, Nieke Van Rhijn, Irma de Vries, Jan Meulenbelt, Joris H. Robben

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


The use of intravenous lipid emulsions (ILE) in human clinical toxicology has become a common practice as life-saving treatment for cardiotoxicity after local anesthetics overdose. Case reports indicate ILE may be useful in the resuscitation from toxicity induced by a variety of other lipophilic cardiotoxic drugs like various tricyclic antidepressants (TCA), lipofilic g-blockers and calcium channel blockers. Several veterinary case reports have demonstrated that ILE are primarily used in the management of long-lasting neurotoxicity like permethrin toxicosis in cats and ivermectin toxicosis in dogs. Treatment with ILE can result in a faster recovery leading to shorter admission times in the veterinary practice. Practical guidelines for the use of ILE during the treatment of intoxications will be given here.

Original languageEnglish
Pages (from-to)22-+
Number of pages5
JournalTijdschrift voor Diergeneeskunde
Issue number6
Publication statusPublished - 1 Jun 2015


  • intravenous lipid emulsion (ILE)
  • lipophilic drug intoxications
  • poisoning
  • cardiotoxicity
  • neurotoxicity


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