Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs

Inge J.M. Slenter; Sylvia C. Djajadiningrat-Laanen; Irma de Vries; Marieke A. Dijkman

doi:10.1016/j.toxcx.2019.100014

Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs

Inge J.M. Slenter^*, Sylvia C. Djajadiningrat-Laanen, Irma de Vries, Marieke A. Dijkman

^*Corresponding author for this work

Clinical Toxicology

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Abstract

We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of Ornithogalum plant material can be potentially life-threatening to companion animals. Further studies are necessary to confirm the involvement of cardiac glycoside-like toxins present in Ornithogalum arabicum and the toxicity of these substances to the retina.

Original language	English
Article number	100014
Journal	Toxicon: X
Volume	4
DOIs	https://doi.org/10.1016/j.toxcx.2019.100014
Publication status	Published - Oct 2019

Keywords

Blindness
Cardiac glycosides
Ornithogalum arabicum
Retinal degeneration

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10.1016/j.toxcx.2019.100014Licence: CC BY-NC-ND

1-s2.0-S2590171019300116-mainFinal published version, 1.25 MBLicence: CC BY-NC-ND

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title = "Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs",

abstract = "We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of Ornithogalum plant material can be potentially life-threatening to companion animals. Further studies are necessary to confirm the involvement of cardiac glycoside-like toxins present in Ornithogalum arabicum and the toxicity of these substances to the retina.",

keywords = "Blindness, Cardiac glycosides, Ornithogalum arabicum, Retinal degeneration",

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AU - de Vries, Irma

AU - Dijkman, Marieke A.

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N2 - We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of Ornithogalum plant material can be potentially life-threatening to companion animals. Further studies are necessary to confirm the involvement of cardiac glycoside-like toxins present in Ornithogalum arabicum and the toxicity of these substances to the retina.

AB - We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of Ornithogalum plant material can be potentially life-threatening to companion animals. Further studies are necessary to confirm the involvement of cardiac glycoside-like toxins present in Ornithogalum arabicum and the toxicity of these substances to the retina.

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Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs

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