INTIMA-MEDIADIKTE VAN DE A. CAROTIS ALS INDICATOR VAN CARDIOVASCULAIR RISICO BIJ OUDEREN; HET ERGO-ONDERZOEK

Translated title of the contribution: Common carotid intima-media thickness and cardiovascular risk; the Rotterdam study

M. L. Bots*, A. Hofman, H. A.P. Pols, P. T.V.M. De Jong, D. E. Grobbee

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Abstract

Objective: To assess the association between common carotid intima-media thickness and several indicators of cardiovascular risk in elderly persons (≥ 55 years). Setting. The suburb of Ommoord in Rotterdam, the Netherlands. Design. Cross-sectional study. Method. In the first 1000 participants of a single-centre population-based cohort study (the Rotterdam Study), ultrasonography of both carotid arteries was performed, peripheral atherosclerosis was assessed by determination of the ankle-arm systolic blood pressure index, and information on cardiovascular history and risk factors was obtained. Results. Increasing age, male gender, a decreased serum HDL cholesterol level and presence of hypertension were significantly associated with an increased common carotid intima-media thickness. An increased body mass index was related to intima-media thickness in men only. Current smoking was associated with an increased intima-media thickness (p = 0.06). No association was found for serum total cholesterol. Subjects with a history of cardiovascular disease had a significantly increased intima-media thickness. An increase in common carotid intima-media thickness was associated with a decrease in ankle-arm index. Conclusion. An increased common carotid intima-media thickness is an indicator of atherosclerosis elsewhere in the arterial system and of cardiovascular risk.

Translated title of the contributionCommon carotid intima-media thickness and cardiovascular risk; the Rotterdam study
Original languageDutch
Pages (from-to)550-555
Number of pages6
JournalNederlands Tijdschrift voor Geneeskunde
Volume140
Issue number10
Publication statusPublished - 9 Mar 1996

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