Abstract
The Hippo signaling pathway exerts a growth-suppressive effect by inhibitory phosphorylation of the oncogenic transcription co-activator Yki/YAP. A recent study paradoxically reports that genetic removal of YAP enhances intestinal stem cell expansion and regeneration.
| Translated title of the contribution | Intestinal regeneration: YAP-tumor suppressor and oncoprotein? |
|---|---|
| Original language | Undefined/Unknown |
| Pages (from-to) | R110-2 |
| Number of pages | 3 |
| Journal | Current Biology |
| Volume | 23 |
| Issue number | 3 |
| Publication status | Published - 2013 |