Insights from Living Myocardial Slices into Chemotherapy-Induced Cardiotoxicity: A Novel Ex Vivo Tool to Guide Clinical Decision-Making

Ilse R. Kelters; Jort S.A. Van Der Geest; Peter Paul M. Zwetsloot; Maarten Jan Cramer; Manon G. Van Der Meer; Niels P. Van Der Kaaij; Jan Peter Van Tintelen; Joost P.G. Sluijter; Vasco Sampaio-Pinto; Linda W. Van Laake

doi:10.1161/CIRCHEARTFAILURE.124.011876

Insights from Living Myocardial Slices into Chemotherapy-Induced Cardiotoxicity: A Novel Ex Vivo Tool to Guide Clinical Decision-Making

Ilse R. Kelters
, Jort S.A. Van Der Geest
, Peter Paul M. Zwetsloot
, Maarten Jan Cramer
, Manon G. Van Der Meer
, Niels P. Van Der Kaaij
, Jan Peter Van Tintelen
, Joost P.G. Sluijter
, Vasco Sampaio-Pinto
, Linda W. Van Laake^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	e011876
Journal	Circulation: Heart Failure
Volume	18
Issue number	5
DOIs	https://doi.org/10.1161/CIRCHEARTFAILURE.124.011876
Publication status	Published - May 2025

Keywords

anthracyclines
carcinoma
cardio-oncology
cardiotoxicity
heart failure
trastuzumab

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10.1161/CIRCHEARTFAILURE.124.011876

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Kelters, I. R., Van Der Geest, J. S. A., Zwetsloot, P. P. M., Cramer, M. J., Van Der Meer, M. G., Van Der Kaaij, N. P., Van Tintelen, J. P., Sluijter, J. P. G., Sampaio-Pinto, V., & Van Laake, L. W. (2025). Insights from Living Myocardial Slices into Chemotherapy-Induced Cardiotoxicity: A Novel Ex Vivo Tool to Guide Clinical Decision-Making. Circulation: Heart Failure, 18(5), Article e011876. https://doi.org/10.1161/CIRCHEARTFAILURE.124.011876

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title = "Insights from Living Myocardial Slices into Chemotherapy-Induced Cardiotoxicity: A Novel Ex Vivo Tool to Guide Clinical Decision-Making",

keywords = "anthracyclines, carcinoma, cardio-oncology, cardiotoxicity, heart failure, trastuzumab",

author = "Kelters, \{Ilse R.\} and \{Van Der Geest\}, \{Jort S.A.\} and Zwetsloot, \{Peter Paul M.\} and Cramer, \{Maarten Jan\} and \{Van Der Meer\}, \{Manon G.\} and \{Van Der Kaaij\}, \{Niels P.\} and \{Van Tintelen\}, \{Jan Peter\} and Sluijter, \{Joost P.G.\} and Vasco Sampaio-Pinto and \{Van Laake\}, \{Linda W.\}",

year = "2025",

month = may,

doi = "10.1161/CIRCHEARTFAILURE.124.011876",

language = "English",

volume = "18",

journal = "Circulation: Heart Failure",

issn = "1941-3289",

publisher = "Lippincott Williams \& Wilkins",

number = "5",

}

Kelters, IR, Van Der Geest, JSA, Zwetsloot, PPM, Cramer, MJ, Van Der Meer, MG, Van Der Kaaij, NP , Van Tintelen, JP , Sluijter, JPG , Sampaio-Pinto, V & Van Laake, LW 2025, 'Insights from Living Myocardial Slices into Chemotherapy-Induced Cardiotoxicity: A Novel Ex Vivo Tool to Guide Clinical Decision-Making', Circulation: Heart Failure, vol. 18, no. 5, e011876. https://doi.org/10.1161/CIRCHEARTFAILURE.124.011876

TY - JOUR

T1 - Insights from Living Myocardial Slices into Chemotherapy-Induced Cardiotoxicity

T2 - A Novel Ex Vivo Tool to Guide Clinical Decision-Making

AU - Kelters, Ilse R.

AU - Van Der Geest, Jort S.A.

AU - Zwetsloot, Peter Paul M.

AU - Cramer, Maarten Jan

AU - Van Der Meer, Manon G.

AU - Van Der Kaaij, Niels P.

AU - Van Tintelen, Jan Peter

AU - Sluijter, Joost P.G.

AU - Sampaio-Pinto, Vasco

AU - Van Laake, Linda W.

PY - 2025/5

Y1 - 2025/5

KW - anthracyclines

KW - carcinoma

KW - cardio-oncology

KW - cardiotoxicity

KW - heart failure

KW - trastuzumab

UR - https://www.scopus.com/pages/publications/105001969571

U2 - 10.1161/CIRCHEARTFAILURE.124.011876

DO - 10.1161/CIRCHEARTFAILURE.124.011876

M3 - Article

AN - SCOPUS:105001969571

SN - 1941-3289

VL - 18

JO - Circulation: Heart Failure

JF - Circulation: Heart Failure

IS - 5

M1 - e011876

ER -

Insights from Living Myocardial Slices into Chemotherapy-Induced Cardiotoxicity: A Novel Ex Vivo Tool to Guide Clinical Decision-Making

Keywords

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