Injectable and adhesive hydrogels for dealing with wounds

Parisa Ghandforoushan, Nasim Golafshan, Firoz Babu Kadumudi, Miguel Castilho, Alireza Dolatshahi-Pirouz, Gorka Orive*

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    1 Citation (Scopus)


    Introduction: The development of wound dressing materials that combine healing properties, ability to self-repair the material damages, skin-friendly adhesive nature, and competent mechanical properties have surpassing functional importance in healthcare. Due to their specificity, hydrogels have been recognized as a new gateway in biological materials to treat dysfunctional tissues. The design and creation of injectable hydrogel-based scaffolds have extensively progressed in recent years to improve their therapeutic efficacy and to pave the way for their easy minimally invasive administration. Hence, injectable hydrogel biomaterials have been prepared to eventually translate into minimally invasive therapy and pose a lasting effect on regenerative medicine. Areas Covered: This review highlights the recent development of adhesive and injectable hydrogels that have applications in wound healing and wound dressing. Such hydrogel materials are not only expected to improve therapeutic outcomes but also to facilitate the easy surgical process in both wound healing and dressing. Expert Opinion: Wound healing seems to be an appealing approach for treating countless life-threatening disorders. With the average increase of life expectancy in human societies, an increase in demand for injectable skin replacements and drug delivery carriers for chronic wound healing is expected.

    Original languageEnglish
    Pages (from-to)519-533
    Number of pages15
    JournalExpert Opinion on Biological Therapy
    Issue number4
    Publication statusPublished - 3 Apr 2022


    • Adhesive
    • biomaterials
    • injectable hydrogel
    • medical applications
    • tissue engineering
    • wound healing


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