TY - JOUR
T1 - Injectable and adhesive hydrogels for dealing with wounds
AU - Ghandforoushan, Parisa
AU - Golafshan, Nasim
AU - Babu Kadumudi, Firoz
AU - Castilho, Miguel
AU - Dolatshahi-Pirouz, Alireza
AU - Orive, Gorka
N1 - Funding Information:
G Orive wishes to thank the Spanish Ministry of Economy, Industry (University of the Basque Country), and Competitiveness (SAF2016-76150-R and BFU2017?82421-P) and technical assistance from the ICTS NANBIOSIS (Drug Formulation Unit, U10) at the University of the Basque Country. We also appreciate the support from the Basque Country Government (Grupos Consolidados, No ref: IT907-16). We also appreciate the support from the Basque Country Government (Grupos Consolidados, No ref: IT907-16). This work has received funding from the European Union?s Horizon 2020 research and innovationprogramme under grant agreement No 951747. Also, this study was supported by a grant from Tabriz University of Medical Sciences, Tabriz, Iran (Grant No: 64103).
Publisher Copyright:
© 2021 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022/4/3
Y1 - 2022/4/3
N2 - Introduction: The development of wound dressing materials that combine healing properties, ability to self-repair the material damages, skin-friendly adhesive nature, and competent mechanical properties have surpassing functional importance in healthcare. Due to their specificity, hydrogels have been recognized as a new gateway in biological materials to treat dysfunctional tissues. The design and creation of injectable hydrogel-based scaffolds have extensively progressed in recent years to improve their therapeutic efficacy and to pave the way for their easy minimally invasive administration. Hence, injectable hydrogel biomaterials have been prepared to eventually translate into minimally invasive therapy and pose a lasting effect on regenerative medicine. Areas Covered: This review highlights the recent development of adhesive and injectable hydrogels that have applications in wound healing and wound dressing. Such hydrogel materials are not only expected to improve therapeutic outcomes but also to facilitate the easy surgical process in both wound healing and dressing. Expert Opinion: Wound healing seems to be an appealing approach for treating countless life-threatening disorders. With the average increase of life expectancy in human societies, an increase in demand for injectable skin replacements and drug delivery carriers for chronic wound healing is expected.
AB - Introduction: The development of wound dressing materials that combine healing properties, ability to self-repair the material damages, skin-friendly adhesive nature, and competent mechanical properties have surpassing functional importance in healthcare. Due to their specificity, hydrogels have been recognized as a new gateway in biological materials to treat dysfunctional tissues. The design and creation of injectable hydrogel-based scaffolds have extensively progressed in recent years to improve their therapeutic efficacy and to pave the way for their easy minimally invasive administration. Hence, injectable hydrogel biomaterials have been prepared to eventually translate into minimally invasive therapy and pose a lasting effect on regenerative medicine. Areas Covered: This review highlights the recent development of adhesive and injectable hydrogels that have applications in wound healing and wound dressing. Such hydrogel materials are not only expected to improve therapeutic outcomes but also to facilitate the easy surgical process in both wound healing and dressing. Expert Opinion: Wound healing seems to be an appealing approach for treating countless life-threatening disorders. With the average increase of life expectancy in human societies, an increase in demand for injectable skin replacements and drug delivery carriers for chronic wound healing is expected.
KW - Adhesive
KW - biomaterials
KW - injectable hydrogel
KW - medical applications
KW - tissue engineering
KW - wound healing
UR - http://www.scopus.com/inward/record.url?scp=85121121281&partnerID=8YFLogxK
U2 - 10.1080/14712598.2022.2008353
DO - 10.1080/14712598.2022.2008353
M3 - Review article
AN - SCOPUS:85121121281
SN - 1471-2598
VL - 22
SP - 519
EP - 533
JO - Expert Opinion on Biological Therapy
JF - Expert Opinion on Biological Therapy
IS - 4
ER -