Influence of a skin allograft on frequencies of CTL precursor in peripheral blood of the dog

W. A. Buurman; G. Groenewegen; C. J. van der Linden; A. J.J.M. Daemen; R. Doveren; G. Kootstra

doi:10.1097/00007890-198408000-00017

Influence of a skin allograft on frequencies of CTL precursor in peripheral blood of the dog

W. A. Buurman, G. Groenewegen, C. J. van der Linden, A. J.J.M. Daemen, R. Doveren, G. Kootstra

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2 Citations (Scopus)

Abstract

Alloantigen-specific cytotoxic T lymphocytes (CTL) and their precursors (CTL-P) have been determined in the peripheral blood of skin allografted dogs. CTL-P frequencies increased rapidly after transplantation and reached maximal values after complete rejection of the skin allograft. Differences in the time response kinetics of CTL-P frequencies between recipients were not correlated with the length of graft survival. The CTL-P frequencies declined after days 13–20 and appeared still to be elevated 30 days after rejection of the graft.

Original language	English
Pages (from-to)	175-177
Number of pages	3
Journal	Transplantation
Volume	38
Issue number	2
DOIs	https://doi.org/10.1097/00007890-198408000-00017
Publication status	Published - 1 Jan 1984

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abstract = "Alloantigen-specific cytotoxic T lymphocytes (CTL) and their precursors (CTL-P) have been determined in the peripheral blood of skin allografted dogs. CTL-P frequencies increased rapidly after transplantation and reached maximal values after complete rejection of the skin allograft. Differences in the time response kinetics of CTL-P frequencies between recipients were not correlated with the length of graft survival. The CTL-P frequencies declined after days 13–20 and appeared still to be elevated 30 days after rejection of the graft.",

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AU - Groenewegen, G.

AU - van der Linden, C. J.

AU - Daemen, A. J.J.M.

AU - Doveren, R.

AU - Kootstra, G.

PY - 1984/1/1

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N2 - Alloantigen-specific cytotoxic T lymphocytes (CTL) and their precursors (CTL-P) have been determined in the peripheral blood of skin allografted dogs. CTL-P frequencies increased rapidly after transplantation and reached maximal values after complete rejection of the skin allograft. Differences in the time response kinetics of CTL-P frequencies between recipients were not correlated with the length of graft survival. The CTL-P frequencies declined after days 13–20 and appeared still to be elevated 30 days after rejection of the graft.

AB - Alloantigen-specific cytotoxic T lymphocytes (CTL) and their precursors (CTL-P) have been determined in the peripheral blood of skin allografted dogs. CTL-P frequencies increased rapidly after transplantation and reached maximal values after complete rejection of the skin allograft. Differences in the time response kinetics of CTL-P frequencies between recipients were not correlated with the length of graft survival. The CTL-P frequencies declined after days 13–20 and appeared still to be elevated 30 days after rejection of the graft.

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ER -

Influence of a skin allograft on frequencies of CTL precursor in peripheral blood of the dog

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