Incidentie van darmkanker stijgt bij jonge mensen in Nederland: Reden tot zorg?

Marloes A.G. Elferink; Laskarina J.K. Galanos; Femke P.C. Sijtsma; Maarten J. Bijlsma; Tineke E. Buffart; Ignace H.J.T. de Hingh; Monique E. van Leerdam; Felice N. van Erning

Incidentie van darmkanker stijgt bij jonge mensen in Nederland: Reden tot zorg?

Translated title of the contribution: Incidence of bowel cancer is rising among young people in the Netherlands: Cause for concern?

Marloes A.G. Elferink^*
, Laskarina J.K. Galanos
, Femke P.C. Sijtsma
, Maarten J. Bijlsma
, Tineke E. Buffart
, Ignace H.J.T. de Hingh
, Monique E. van Leerdam
, Felice N. van Erning

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Objective

To describe trends in incidence of early-onset colorectal cancer in the Netherlands.

Design

Observational research

Method

We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035.

Results

The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035.

Conclusion

There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.

Translated title of the contribution	Incidence of bowel cancer is rising among young people in the Netherlands: Cause for concern?
Original language	Dutch
Article number	D8529
Pages (from-to)	19-23
Number of pages	5
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	169
Issue number	5
Publication status	Published - 24 Apr 2025

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https://www.ntvg.nl/artikelen/incidentie-van-darmkanker-stijgt-bij-jonge-mensen-nederland#

Cite this

Elferink, M. A. G., Galanos, L. J. K., Sijtsma, F. P. C., Bijlsma, M. J., Buffart, T. E., de Hingh, I. H. J. T., van Leerdam, M. E., & van Erning, F. N. (2025). Incidentie van darmkanker stijgt bij jonge mensen in Nederland: Reden tot zorg? Nederlands Tijdschrift voor Geneeskunde, 169(5), 19-23. Article D8529. https://www.ntvg.nl/artikelen/incidentie-van-darmkanker-stijgt-bij-jonge-mensen-nederland#

@article{46513ba0c15645289c9fb04be8ac1420,

title = "Incidentie van darmkanker stijgt bij jonge mensen in Nederland: Reden tot zorg?",

abstract = "Objective To describe trends in incidence of early-onset colorectal cancer in the Netherlands. Design Observational research Method We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035. Results The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41\% (95\% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035. Conclusion There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.",

author = "Elferink, \{Marloes A.G.\} and Galanos, \{Laskarina J.K.\} and Sijtsma, \{Femke P.C.\} and Bijlsma, \{Maarten J.\} and Buffart, \{Tineke E.\} and \{de Hingh\}, \{Ignace H.J.T.\} and \{van Leerdam\}, \{Monique E.\} and \{van Erning\}, \{Felice N.\}",

year = "2025",

month = apr,

day = "24",

language = "Dutch",

volume = "169",

pages = "19--23",

journal = "Nederlands Tijdschrift voor Geneeskunde",

issn = "0028-2162",

publisher = "Vereniging Nederlands Tijdschrift voor Geneeskunde",

number = "5",

}

Elferink, MAG, Galanos, LJK, Sijtsma, FPC, Bijlsma, MJ, Buffart, TE, de Hingh, IHJT, van Leerdam, ME & van Erning, FN 2025, 'Incidentie van darmkanker stijgt bij jonge mensen in Nederland: Reden tot zorg?', Nederlands Tijdschrift voor Geneeskunde, vol. 169, no. 5, D8529, pp. 19-23. <https://www.ntvg.nl/artikelen/incidentie-van-darmkanker-stijgt-bij-jonge-mensen-nederland#>

TY - JOUR

T1 - Incidentie van darmkanker stijgt bij jonge mensen in Nederland

T2 - Reden tot zorg?

AU - Elferink, Marloes A.G.

AU - Galanos, Laskarina J.K.

AU - Sijtsma, Femke P.C.

AU - Bijlsma, Maarten J.

AU - Buffart, Tineke E.

AU - de Hingh, Ignace H.J.T.

AU - van Leerdam, Monique E.

AU - van Erning, Felice N.

PY - 2025/4/24

Y1 - 2025/4/24

N2 - Objective To describe trends in incidence of early-onset colorectal cancer in the Netherlands. Design Observational research Method We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035. Results The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035. Conclusion There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.

AB - Objective To describe trends in incidence of early-onset colorectal cancer in the Netherlands. Design Observational research Method We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035. Results The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035. Conclusion There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.

UR - https://www.scopus.com/pages/publications/105032393088

M3 - Article

AN - SCOPUS:105032393088

SN - 0028-2162

VL - 169

SP - 19

EP - 23

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

IS - 5

M1 - D8529

ER -

Incidentie van darmkanker stijgt bij jonge mensen in Nederland: Reden tot zorg?

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