TY - JOUR
T1 - In-vitro activity of a new quinolone (CP-99, 219) compared with ciprofloxacin, pefloxacin, azithromycin and penicillin against neisseria gonorrhoeae
AU - Van Rijsoort-vos, J. H.
AU - Stolz, E.
AU - Verbnigh, H. A.
AU - Kluytmans, J. A.J.W.
PY - 1995/7
Y1 - 1995/7
N2 - The in-vitro activities of CP-99, 219, ciprofloxacin, pefloxacin, azithromycin and penicillin was tested against 114 Neisseria gonorrhoeae strains. The MIG90s were: 0.008 mg/L (MIC range 0.001-0.06 mg/L) for CP-99, 219, 0.008 mg/L (MIC range 0.001-0.25 mg/L) for ciprofloxacin, 0.12 mg/L (MIC range 0.008-4 mg/L) for pefloxacin, 0.25 mg/L (MIC range 0.03-1 mg/L) for azithromycin and 16mg/L (MIC range 0.015-16 mg/L) for penicillin. The activity of CP-99, 219 against various N. gonorrhoeae isolates was comparable to ciprofloxacin.
AB - The in-vitro activities of CP-99, 219, ciprofloxacin, pefloxacin, azithromycin and penicillin was tested against 114 Neisseria gonorrhoeae strains. The MIG90s were: 0.008 mg/L (MIC range 0.001-0.06 mg/L) for CP-99, 219, 0.008 mg/L (MIC range 0.001-0.25 mg/L) for ciprofloxacin, 0.12 mg/L (MIC range 0.008-4 mg/L) for pefloxacin, 0.25 mg/L (MIC range 0.03-1 mg/L) for azithromycin and 16mg/L (MIC range 0.015-16 mg/L) for penicillin. The activity of CP-99, 219 against various N. gonorrhoeae isolates was comparable to ciprofloxacin.
UR - http://www.scopus.com/inward/record.url?scp=0029097001&partnerID=8YFLogxK
U2 - 10.1093/jac/36.1.215
DO - 10.1093/jac/36.1.215
M3 - Article
C2 - 8537268
AN - SCOPUS:0029097001
SN - 0305-7453
VL - 36
SP - 215
EP - 218
JO - Journal of Antimicrobial Chemotherapy
JF - Journal of Antimicrobial Chemotherapy
IS - 1
ER -