Abstract
The in vitro susceptibilities of 24 worldwide Exserohilum isolates belonging to 10 species from human and environmental sources were determined for eight antifungal drugs. The strains were characterized by internal transcribed spacer (ITS) sequencing and amplified fragment length polymorphism fingerprinting. Posaconazole had the lowest geometric mean MIC (0.16 μg/ml), followed by micafungin (0.21 μg/ml), amphotericin B (0.24 μg/ml), itraconazole (0.33 μg/ml), voriconazole (0.8 μg/ml), caspofungin (1.05 μg/ml), isavuconazole (1.38 μg/ml), and fluconazole (15.6 μg/ml).
| Original language | English |
|---|---|
| Pages (from-to) | 6642-5 |
| Number of pages | 4 |
| Journal | Antimicrobial Agents and Chemotherapy |
| Volume | 59 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 2015 |
| Externally published | Yes |
Keywords
- Amphotericin B/pharmacology
- Amplified Fragment Length Polymorphism Analysis
- Antifungal Agents
- Ascomycota/drug effects
- Caspofungin
- Echinocandins/pharmacology
- Fluconazole/pharmacology
- Genotype
- Itraconazole/pharmacology
- Lipopeptides/pharmacology
- Micafungin
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Nitriles/pharmacology
- Pyridines/pharmacology
- Triazoles/pharmacology
- Voriconazole/pharmacology
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