In-Hospital Production of Medicines: Preparing for Disruption

Shona Kalkman; Marlous Arentshorst; Jarno Hoekman; Wouter Boon; Esther Uijtendaal; Ghislaine van Thiel; Ellen Moors

doi:10.1016/j.tibtech.2019.09.011

In-Hospital Production of Medicines: Preparing for Disruption

Shona Kalkman, Marlous Arentshorst, Jarno Hoekman, Wouter Boon, Esther Uijtendaal, Ghislaine van Thiel, Ellen Moors

Research output: Contribution to journal › Short survey › peer-review

2 Citations (Scopus)

Abstract

In-hospital production of affordable medicines holds potential to address problems of drug accessibility. However, expanding the scope of magistral preparation to include high-cost drugs and complex biologicals gives rise to new challenges. We discuss ethical and regulatory complexities faced by Dutch initiatives defying the current pharmaceutical system through magistral preparation.

Original language	English
Pages (from-to)	1045-1047
Number of pages	3
Journal	Trends in biotechnology
Volume	38
Issue number	10
Early online date	31 Oct 2019
DOIs	https://doi.org/10.1016/j.tibtech.2019.09.011
Publication status	Published - Oct 2020

Keywords

disruptive innovation
ethics
in-hospital production
magistral preparation
regulatory science

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10.1016/j.tibtech.2019.09.011

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title = "In-Hospital Production of Medicines: Preparing for Disruption",

abstract = "In-hospital production of affordable medicines holds potential to address problems of drug accessibility. However, expanding the scope of magistral preparation to include high-cost drugs and complex biologicals gives rise to new challenges. We discuss ethical and regulatory complexities faced by Dutch initiatives defying the current pharmaceutical system through magistral preparation.",

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author = "Shona Kalkman and Marlous Arentshorst and Jarno Hoekman and Wouter Boon and Esther Uijtendaal and {van Thiel}, Ghislaine and Ellen Moors",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2020",

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language = "English",

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T1 - In-Hospital Production of Medicines

T2 - Preparing for Disruption

AU - Kalkman, Shona

AU - Arentshorst, Marlous

AU - Hoekman, Jarno

AU - Boon, Wouter

AU - Uijtendaal, Esther

AU - van Thiel, Ghislaine

AU - Moors, Ellen

PY - 2020/10

Y1 - 2020/10

N2 - In-hospital production of affordable medicines holds potential to address problems of drug accessibility. However, expanding the scope of magistral preparation to include high-cost drugs and complex biologicals gives rise to new challenges. We discuss ethical and regulatory complexities faced by Dutch initiatives defying the current pharmaceutical system through magistral preparation.

AB - In-hospital production of affordable medicines holds potential to address problems of drug accessibility. However, expanding the scope of magistral preparation to include high-cost drugs and complex biologicals gives rise to new challenges. We discuss ethical and regulatory complexities faced by Dutch initiatives defying the current pharmaceutical system through magistral preparation.

KW - disruptive innovation

KW - ethics

KW - in-hospital production

KW - magistral preparation

KW - regulatory science

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U2 - 10.1016/j.tibtech.2019.09.011

DO - 10.1016/j.tibtech.2019.09.011

M3 - Short survey

C2 - 31679825

SN - 0167-7799

VL - 38

SP - 1045

EP - 1047

JO - Trends in biotechnology

JF - Trends in biotechnology

IS - 10

ER -

In-Hospital Production of Medicines: Preparing for Disruption

Abstract

Keywords

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