Improved diagnostic validity of the ADOS revised algorithms: A replication study in an independent sample

I. Oosterling, S. Roos, A. de Bildt, N. Rommelse, M.V. de Jonge, J. Visser, M. Lappenschaar, S. Swinkels, R.J. van der Gaag, J. Buitelaar

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Abstract

Recently, Gotham et al. (2007) proposed revised algorithms for the Autism Diagnostic Observation Schedule (ADOS) with improved diagnostic validity. The aim of the current study was to replicate predictive validity, factor structure, and correlations with age and verbal and nonverbal IQ of the ADOS revised algorithms for Modules 1 and 2 in a large independent Dutch sample (N = 532). Results showed that the improvement of diagnostic validity was most apparent for autism, except in very young or low functioning children. Results for other autism spectrum disorders were less consistent. Overall, these findings support the use of the more homogeneous revised algorithms, with the use of similar items across developmental cells making it easier to compare ADOS scores within and between individuals.

Original languageEnglish
Pages (from-to)689-703
Number of pages15
JournalJournal of Autism and Developmental Disorders
Volume40
Issue number6
DOIs
Publication statusPublished - 1 Jun 2010

Keywords

  • ADOS
  • Algorithm
  • Autism
  • Diagnosis
  • Sensitivity
  • Specificity

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