Impact of vomiting on P2Y12 platelet inhibition in patients with ST-elevation myocardial infarction: A prespecified subanalysis of the ON-TIME 3 trial

doi:10.1016/j.ahj.2021.08.011

Impact of vomiting on P2Y12 platelet inhibition in patients with ST-elevation myocardial infarction: A prespecified subanalysis of the ON-TIME 3 trial

Research output: Contribution to journal › Letter › Academic › peer-review

Abstract

Vomiting is associated with lower levels of ticagrelor concentration and higher platelet reactivity in the early hours of ST-elevation myocardial infarction. These results support reloading with a ticagrelor loading dose and/or treatment with intravenous platelet inhibitors when patients vomit.

Original language	English
Pages (from-to)	39-42
Number of pages	4
Journal	American Heart Journal
Volume	243
DOIs	https://doi.org/10.1016/j.ahj.2021.08.011
Publication status	Published - Jan 2022
Externally published	Yes

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10.1016/j.ahj.2021.08.011

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@article{d942364199f742a1a090ec5523b4860e,

title = "Impact of vomiting on P2Y12 platelet inhibition in patients with ST-elevation myocardial infarction: A prespecified subanalysis of the ON-TIME 3 trial",

abstract = "Vomiting is associated with lower levels of ticagrelor concentration and higher platelet reactivity in the early hours of ST-elevation myocardial infarction. These results support reloading with a ticagrelor loading dose and/or treatment with intravenous platelet inhibitors when patients vomit.",

author = "Tavenier, \{Anne  H H.\} and Hermanides, \{Renicus  S S.\} and Ottervanger, \{Jan  Paul P.\} and Belitser, \{Svetlana  V V.\} and Klungel, \{Olaf   H\} and \{van {\textquoteleft}t Hof\}, \{Arnoud  W W.J.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2022",

month = jan,

doi = "10.1016/j.ahj.2021.08.011",

language = "English",

volume = "243",

pages = "39--42",

journal = "American Heart Journal",

issn = "0002-8703",

publisher = "Elsevier",

}

TY - JOUR

T1 - Impact of vomiting on P2Y12 platelet inhibition in patients with ST-elevation myocardial infarction

T2 - A prespecified subanalysis of the ON-TIME 3 trial

AU - Tavenier, Anne  H H.

AU - Hermanides, Renicus  S S.

AU - Ottervanger, Jan  Paul P.

AU - Belitser, Svetlana  V V.

AU - Klungel, Olaf   H

AU - van ‘t Hof, Arnoud  W W.J.

PY - 2022/1

Y1 - 2022/1

N2 - Vomiting is associated with lower levels of ticagrelor concentration and higher platelet reactivity in the early hours of ST-elevation myocardial infarction. These results support reloading with a ticagrelor loading dose and/or treatment with intravenous platelet inhibitors when patients vomit.

AB - Vomiting is associated with lower levels of ticagrelor concentration and higher platelet reactivity in the early hours of ST-elevation myocardial infarction. These results support reloading with a ticagrelor loading dose and/or treatment with intravenous platelet inhibitors when patients vomit.

UR - https://www.scopus.com/pages/publications/85122487846

U2 - 10.1016/j.ahj.2021.08.011

DO - 10.1016/j.ahj.2021.08.011

M3 - Letter

C2 - 34547260

AN - SCOPUS:85122487846

SN - 0002-8703

VL - 243

SP - 39

EP - 42

JO - American Heart Journal

JF - American Heart Journal

ER -

Impact of vomiting on P2Y12 platelet inhibition in patients with ST-elevation myocardial infarction: A prespecified subanalysis of the ON-TIME 3 trial

Abstract

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