Imaging the myocardial ischemic cascade

Arthur E Stillman; Matthijs Oudkerk; David A Bluemke; Menko Jan de Boer; Jens Bremerich; Ernest V Garcia; Matthias Gutberlet; Pim van der Harst; W Gregory Hundley; Michael Jerosch-Herold; Dirkjan Kuijpers; Raymond Y Kwong; Eike Nagel; Stamatios Lerakis; John Oshinski; Jean-François Paul; Riemer H J A Slart; Vinod Thourani; Rozemarijn Vliegenthart; Bernd J Wintersperger

doi:10.1007/s10554-018-1330-4

Imaging the myocardial ischemic cascade

Arthur E Stillman, Matthijs Oudkerk, David A Bluemke, Menko Jan de Boer, Jens Bremerich, Ernest V Garcia, Matthias Gutberlet, Pim van der Harst, W Gregory Hundley, Michael Jerosch-Herold, Dirkjan Kuijpers, Raymond Y Kwong, Eike Nagel, Stamatios Lerakis, John Oshinski, Jean-François Paul, Riemer H J A Slart, Vinod Thourani, Rozemarijn Vliegenthart, Bernd J Wintersperger

Research output: Contribution to journal › Review article › peer-review

Abstract

Non-invasive imaging plays a growing role in the diagnosis and management of ischemic heart disease from its earliest manifestations of endothelial dysfunction to myocardial infarction along the myocardial ischemic cascade. Experts representing the North American Society for Cardiovascular Imaging and the European Society of Cardiac Radiology have worked together to organize the role of non-invasive imaging along the framework of the ischemic cascade. The current status of non-invasive imaging for ischemic heart disease is reviewed along with the role of imaging for guiding surgical planning. The issue of cost effectiveness is also considered. Preclinical disease is primarily assessed through the coronary artery calcium score and used for risk assessment. Once the patient becomes symptomatic, other imaging tests including echocardiography, CCTA, SPECT, PET and CMR may be useful. CCTA appears to be a cost-effective gatekeeper. Post infarction CMR and PET are the preferred modalities. Imaging is increasingly used for surgical planning of patients who may require coronary artery bypass.

Original language	English
Pages (from-to)	1249-1263
Number of pages	15
Journal	The International Journal of Cardiovascular Imaging
Volume	34
Issue number	8
DOIs	https://doi.org/10.1007/s10554-018-1330-4
Publication status	Published - Aug 2018
Externally published	Yes

Keywords

Angina Pectoris/diagnostic imaging
Cardiac Imaging Techniques/economics
Coronary Artery Disease/complications
Cost-Benefit Analysis
Disease Progression
Endothelium, Vascular/diagnostic imaging
Humans
Myocardial Infarction/diagnostic imaging
Myocardial Ischemia/diagnostic imaging

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10.1007/s10554-018-1330-4

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Stillman, A. E., Oudkerk, M., Bluemke, D. A., de Boer, M. J., Bremerich, J., Garcia, E. V., Gutberlet, M., van der Harst, P., Hundley, W. G., Jerosch-Herold, M., Kuijpers, D., Kwong, R. Y., Nagel, E., Lerakis, S., Oshinski, J., Paul, J.-F., Slart, R. H. J. A., Thourani, V., Vliegenthart, R., & Wintersperger, B. J. (2018). Imaging the myocardial ischemic cascade. The International Journal of Cardiovascular Imaging, 34(8), 1249-1263. https://doi.org/10.1007/s10554-018-1330-4

@article{4cf8b6f010c54c36a5bdd88fbaeb274f,

title = "Imaging the myocardial ischemic cascade",

abstract = "Non-invasive imaging plays a growing role in the diagnosis and management of ischemic heart disease from its earliest manifestations of endothelial dysfunction to myocardial infarction along the myocardial ischemic cascade. Experts representing the North American Society for Cardiovascular Imaging and the European Society of Cardiac Radiology have worked together to organize the role of non-invasive imaging along the framework of the ischemic cascade. The current status of non-invasive imaging for ischemic heart disease is reviewed along with the role of imaging for guiding surgical planning. The issue of cost effectiveness is also considered. Preclinical disease is primarily assessed through the coronary artery calcium score and used for risk assessment. Once the patient becomes symptomatic, other imaging tests including echocardiography, CCTA, SPECT, PET and CMR may be useful. CCTA appears to be a cost-effective gatekeeper. Post infarction CMR and PET are the preferred modalities. Imaging is increasingly used for surgical planning of patients who may require coronary artery bypass.",

keywords = "Angina Pectoris/diagnostic imaging, Cardiac Imaging Techniques/economics, Coronary Artery Disease/complications, Cost-Benefit Analysis, Disease Progression, Endothelium, Vascular/diagnostic imaging, Humans, Myocardial Infarction/diagnostic imaging, Myocardial Ischemia/diagnostic imaging",

author = "Stillman, {Arthur E} and Matthijs Oudkerk and Bluemke, {David A} and {de Boer}, {Menko Jan} and Jens Bremerich and Garcia, {Ernest V} and Matthias Gutberlet and {van der Harst}, Pim and Hundley, {W Gregory} and Michael Jerosch-Herold and Dirkjan Kuijpers and Kwong, {Raymond Y} and Eike Nagel and Stamatios Lerakis and John Oshinski and Jean-Fran{\c c}ois Paul and Slart, {Riemer H J A} and Vinod Thourani and Rozemarijn Vliegenthart and Wintersperger, {Bernd J}",

note = "Publisher Copyright: {\textcopyright} 2018, Springer Science+Business Media B.V., part of Springer Nature.",

year = "2018",

month = aug,

doi = "10.1007/s10554-018-1330-4",

language = "English",

volume = "34",

pages = "1249--1263",

journal = "The International Journal of Cardiovascular Imaging",

issn = "1569-5794",

publisher = "Springer Netherlands",

number = "8",

}

Stillman, AE, Oudkerk, M, Bluemke, DA, de Boer, MJ, Bremerich, J, Garcia, EV, Gutberlet, M, van der Harst, P, Hundley, WG, Jerosch-Herold, M, Kuijpers, D, Kwong, RY, Nagel, E, Lerakis, S, Oshinski, J, Paul, J-F, Slart, RHJA, Thourani, V, Vliegenthart, R & Wintersperger, BJ 2018, 'Imaging the myocardial ischemic cascade', The International Journal of Cardiovascular Imaging, vol. 34, no. 8, pp. 1249-1263. https://doi.org/10.1007/s10554-018-1330-4

TY - JOUR

T1 - Imaging the myocardial ischemic cascade

AU - Stillman, Arthur E

AU - Oudkerk, Matthijs

AU - Bluemke, David A

AU - de Boer, Menko Jan

AU - Bremerich, Jens

AU - Garcia, Ernest V

AU - Gutberlet, Matthias

AU - van der Harst, Pim

AU - Hundley, W Gregory

AU - Jerosch-Herold, Michael

AU - Kuijpers, Dirkjan

AU - Kwong, Raymond Y

AU - Nagel, Eike

AU - Lerakis, Stamatios

AU - Oshinski, John

AU - Paul, Jean-François

AU - Slart, Riemer H J A

AU - Thourani, Vinod

AU - Vliegenthart, Rozemarijn

AU - Wintersperger, Bernd J

PY - 2018/8

Y1 - 2018/8

N2 - Non-invasive imaging plays a growing role in the diagnosis and management of ischemic heart disease from its earliest manifestations of endothelial dysfunction to myocardial infarction along the myocardial ischemic cascade. Experts representing the North American Society for Cardiovascular Imaging and the European Society of Cardiac Radiology have worked together to organize the role of non-invasive imaging along the framework of the ischemic cascade. The current status of non-invasive imaging for ischemic heart disease is reviewed along with the role of imaging for guiding surgical planning. The issue of cost effectiveness is also considered. Preclinical disease is primarily assessed through the coronary artery calcium score and used for risk assessment. Once the patient becomes symptomatic, other imaging tests including echocardiography, CCTA, SPECT, PET and CMR may be useful. CCTA appears to be a cost-effective gatekeeper. Post infarction CMR and PET are the preferred modalities. Imaging is increasingly used for surgical planning of patients who may require coronary artery bypass.

AB - Non-invasive imaging plays a growing role in the diagnosis and management of ischemic heart disease from its earliest manifestations of endothelial dysfunction to myocardial infarction along the myocardial ischemic cascade. Experts representing the North American Society for Cardiovascular Imaging and the European Society of Cardiac Radiology have worked together to organize the role of non-invasive imaging along the framework of the ischemic cascade. The current status of non-invasive imaging for ischemic heart disease is reviewed along with the role of imaging for guiding surgical planning. The issue of cost effectiveness is also considered. Preclinical disease is primarily assessed through the coronary artery calcium score and used for risk assessment. Once the patient becomes symptomatic, other imaging tests including echocardiography, CCTA, SPECT, PET and CMR may be useful. CCTA appears to be a cost-effective gatekeeper. Post infarction CMR and PET are the preferred modalities. Imaging is increasingly used for surgical planning of patients who may require coronary artery bypass.

KW - Angina Pectoris/diagnostic imaging

KW - Cardiac Imaging Techniques/economics

KW - Coronary Artery Disease/complications

KW - Cost-Benefit Analysis

KW - Disease Progression

KW - Endothelium, Vascular/diagnostic imaging

KW - Humans

KW - Myocardial Infarction/diagnostic imaging

KW - Myocardial Ischemia/diagnostic imaging

U2 - 10.1007/s10554-018-1330-4

DO - 10.1007/s10554-018-1330-4

M3 - Review article

C2 - 29556943

SN - 1569-5794

VL - 34

SP - 1249

EP - 1263

JO - The International Journal of Cardiovascular Imaging

JF - The International Journal of Cardiovascular Imaging

IS - 8

ER -

Imaging the myocardial ischemic cascade

Abstract

Keywords

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