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Imaging tests for the diagnosis of COVID-19

  • Matthew D.F. McInnes*
  • , Mariska M.G. Leeflang
  • , Jean Paul Salameh
  • , Trevor A. McGrath
  • , Christian B. van der Pol
  • , Robert A. Frank
  • , Ross Prager
  • , Samanjit S. Hare
  • , Carole Dennie
  • , René Spijker
  • , Jonathan J. Deeks
  • , Jacqueline Dinnes
  • , Kevin Jenniskens
  • , Daniël A. Korevaar
  • , Jérémie F. Cohen
  • , Ann Van den Bruel
  • , Yemisi Takwoingi
  • , Janneke van de Wijgert
  • , Johanna A.A.G. Damen
  • , Lotty Hooft
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

Objectives: This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows:. The primary objective is to determine the diagnostic accuracy of chest imaging (computed tomography (CT), chest X-ray and ultrasound) in the evaluation of people suspected to have COVID-19. This may also refer to specific signs, such as a particular CT finding. Secondary objectives To evaluate whether these imaging tests are sufficiently accurate to rule out COVID-19 (main measure of interest will be the negative predictive value) To evaluate the rate of positive imaging in patients with initial RT-PCR negative results who have a positive result on a follow-up RT-PCR test To determine if there is an association between number of days after symptom onset, symptom severity and the findings on chest imaging for patients with COVID-19 To determine the rate of discrepancy or agreement between CT, chest X-ray and ultrasound findings To evaluate for ‘threshold’ effects of imaging findings of COVID-19 and accuracy measures To determine the rate of alternative diagnoses identified by chest imaging.

Original languageEnglish
Article numberCD013639
JournalCochrane Database of Systematic Reviews
Volume2020
Issue number6
DOIs
Publication statusPublished - 2 Jun 2020

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