TY - JOUR
T1 - Imaging strategies in the management of oesophageal cancer
T2 - What's the role of MRI?
AU - van Rossum, P.S.N.
AU - van Hillegersberg, R.
AU - Lever, F.M.
AU - Lips, I.M.
AU - van Lier, A.L.H.M.W.
AU - Meijer, G.J.
AU - van Leeuwen, M.S.
AU - van Vulpen, M.
AU - Ruurda, J.P.
PY - 2013/7
Y1 - 2013/7
N2 - Objectives: To outline the current role and future potential of magnetic resonance imaging (MRI) in the management of oesophageal cancer regarding T-staging, N-staging, tumour delineation for radiotherapy (RT) and treatment response assessment. Methods: PubMed, Embase and the Cochrane library were searched identifying all articles related to the use of MRI in oesophageal cancer. Data regarding the value of MRI in the areas of interest were extracted in order to calculate sensitivity, specificity, predictive values and accuracy for group-related outcome measures. Results: Although historically poor, recent improvements in MRI protocols and techniques have resulted in better imaging quality and the valuable addition of functional information. In recent studies, similar or even better results have been achieved using optimised MRI compared with other imaging strategies for T- and N-staging. No studies clearly report on the role of MRI in oesophageal tumour delineation and real-time guidance for RT so far. Recent pilot studies showed that functional MRI might be capable of predicting pathological response to treatment and patient prognosis. Conclusions: In the near future MRI has the potential to bring improvement in staging, tumour delineation and real-time guidance for RT and assessment of treatment response, thereby complementing the limitations of currently used imaging strategies.
AB - Objectives: To outline the current role and future potential of magnetic resonance imaging (MRI) in the management of oesophageal cancer regarding T-staging, N-staging, tumour delineation for radiotherapy (RT) and treatment response assessment. Methods: PubMed, Embase and the Cochrane library were searched identifying all articles related to the use of MRI in oesophageal cancer. Data regarding the value of MRI in the areas of interest were extracted in order to calculate sensitivity, specificity, predictive values and accuracy for group-related outcome measures. Results: Although historically poor, recent improvements in MRI protocols and techniques have resulted in better imaging quality and the valuable addition of functional information. In recent studies, similar or even better results have been achieved using optimised MRI compared with other imaging strategies for T- and N-staging. No studies clearly report on the role of MRI in oesophageal tumour delineation and real-time guidance for RT so far. Recent pilot studies showed that functional MRI might be capable of predicting pathological response to treatment and patient prognosis. Conclusions: In the near future MRI has the potential to bring improvement in staging, tumour delineation and real-time guidance for RT and assessment of treatment response, thereby complementing the limitations of currently used imaging strategies.
KW - Diagnostic Imaging
KW - Esophageal Neoplasms
KW - Humans
KW - Lymphatic Metastasis
KW - Magnetic Resonance Imaging
KW - Neoplasm Staging
KW - Prognosis
KW - Tomography, X-Ray Computed
KW - Treatment Outcome
UR - http://www.scopus.com/inward/record.url?scp=84879025356&partnerID=8YFLogxK
U2 - 10.1007/s00330-013-2773-6
DO - 10.1007/s00330-013-2773-6
M3 - Article
C2 - 23404138
SN - 0938-7994
VL - 23
SP - 1753
EP - 1765
JO - European Radiology
JF - European Radiology
IS - 7
ER -