IgE: an immunoglobulin specialized in antigen capture?

G C Mudde; T T Hansel; F C von Reijsen; B F Osterhoff; C A Bruijnzeel-Koomen

IgE: an immunoglobulin specialized in antigen capture?

G C Mudde, T T Hansel, F C von Reijsen, B F Osterhoff, C A Bruijnzeel-Koomen

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

IgE bound to the low-affinity receptor for immunoglobulin E (Fc epsilon R) on antigen-presenting cells (APCs) may permit binding of antigens to APCs prior to their processing and presentation. Here, G. C. Mudde and colleagues argue that the unique characteristics of IgE serological responses together with the distribution of Fc epsilon RII (CD23) on APCs are consistent with this novel function of IgE. The concept of IgE involvement in antigen capture is discussed in relation to Langerhans cells, B cells and follicular dendritic cells.

Original language	English
Pages (from-to)	440-3
Number of pages	4
Journal	Immunology Today
Volume	11
Issue number	12
Publication status	Published - Dec 1990

Keywords

Animals
Antigen-Presenting Cells
Antigens, Differentiation, B-Lymphocyte
Humans
Immunoglobulin E
Immunoglobulin G
Receptors, Fc
Receptors, IgE

Cite this

@article{40384c7c0c2841a491c6f012c5bf005a,

title = "IgE: an immunoglobulin specialized in antigen capture?",

abstract = "IgE bound to the low-affinity receptor for immunoglobulin E (Fc epsilon R) on antigen-presenting cells (APCs) may permit binding of antigens to APCs prior to their processing and presentation. Here, G. C. Mudde and colleagues argue that the unique characteristics of IgE serological responses together with the distribution of Fc epsilon RII (CD23) on APCs are consistent with this novel function of IgE. The concept of IgE involvement in antigen capture is discussed in relation to Langerhans cells, B cells and follicular dendritic cells.",

keywords = "Animals, Antigen-Presenting Cells, Antigens, Differentiation, B-Lymphocyte, Humans, Immunoglobulin E, Immunoglobulin G, Receptors, Fc, Receptors, IgE",

author = "Mudde, {G C} and Hansel, {T T} and {von Reijsen}, {F C} and Osterhoff, {B F} and Bruijnzeel-Koomen, {C A}",

year = "1990",

month = dec,

language = "English",

volume = "11",

pages = "440--3",

journal = "Immunology Today",

issn = "0167-5699",

publisher = "Elsevier",

number = "12",

}

TY - JOUR

T1 - IgE

T2 - an immunoglobulin specialized in antigen capture?

AU - Mudde, G C

AU - Hansel, T T

AU - von Reijsen, F C

AU - Osterhoff, B F

AU - Bruijnzeel-Koomen, C A

PY - 1990/12

Y1 - 1990/12

N2 - IgE bound to the low-affinity receptor for immunoglobulin E (Fc epsilon R) on antigen-presenting cells (APCs) may permit binding of antigens to APCs prior to their processing and presentation. Here, G. C. Mudde and colleagues argue that the unique characteristics of IgE serological responses together with the distribution of Fc epsilon RII (CD23) on APCs are consistent with this novel function of IgE. The concept of IgE involvement in antigen capture is discussed in relation to Langerhans cells, B cells and follicular dendritic cells.

AB - IgE bound to the low-affinity receptor for immunoglobulin E (Fc epsilon R) on antigen-presenting cells (APCs) may permit binding of antigens to APCs prior to their processing and presentation. Here, G. C. Mudde and colleagues argue that the unique characteristics of IgE serological responses together with the distribution of Fc epsilon RII (CD23) on APCs are consistent with this novel function of IgE. The concept of IgE involvement in antigen capture is discussed in relation to Langerhans cells, B cells and follicular dendritic cells.

KW - Animals

KW - Antigen-Presenting Cells

KW - Antigens, Differentiation, B-Lymphocyte

KW - Humans

KW - Immunoglobulin E

KW - Immunoglobulin G

KW - Receptors, Fc

KW - Receptors, IgE

M3 - Article

C2 - 2149931

SN - 0167-5699

VL - 11

SP - 440

EP - 443

JO - Immunology Today

JF - Immunology Today

IS - 12

ER -

IgE: an immunoglobulin specialized in antigen capture?

Abstract

Keywords

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