Identification of a novel genomic island specific to hospital-acquired clonal complex 17 Enterococcus faecium isolates

E. Heikens; W. van Schaik; H.L. Laevis; M.J.M. Bonten; R.J.L. Willems

doi:10.1128/AEM.01378-08

Identification of a novel genomic island specific to hospital-acquired clonal complex 17 Enterococcus faecium isolates

E. Heikens, W. van Schaik, H.L. Laevis, M.J.M. Bonten, R.J.L. Willems

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Hospital-acquired clonal complex 17 (CC17) Enterococcus faecium strains are genetically distinct from indigenous strains and are enriched with resistance genes and virulence genes. We identified a genomic island in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism, which may provide a competitive advantage over the indigenous E. faecium microbiota.

Original language	English
Pages (from-to)	7094-7097
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	74
Issue number	22
DOIs	https://doi.org/10.1128/AEM.01378-08
Publication status	Published - Nov 2008

Keywords

Carbohydrate Metabolism
Cross Infection
Enterococcus faecium
Gene Order
Genes, Bacterial
Genomic Islands
Gram-Positive Bacterial Infections

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10.1128/AEM.01378-08

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title = "Identification of a novel genomic island specific to hospital-acquired clonal complex 17 Enterococcus faecium isolates",

abstract = "Hospital-acquired clonal complex 17 (CC17) Enterococcus faecium strains are genetically distinct from indigenous strains and are enriched with resistance genes and virulence genes. We identified a genomic island in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism, which may provide a competitive advantage over the indigenous E. faecium microbiota.",

keywords = "Carbohydrate Metabolism, Cross Infection, Enterococcus faecium, Gene Order, Genes, Bacterial, Genomic Islands, Gram-Positive Bacterial Infections",

author = "E. Heikens and {van Schaik}, W. and H.L. Laevis and M.J.M. Bonten and R.J.L. Willems",

year = "2008",

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AU - Heikens, E.

AU - van Schaik, W.

AU - Laevis, H.L.

AU - Bonten, M.J.M.

AU - Willems, R.J.L.

PY - 2008/11

Y1 - 2008/11

N2 - Hospital-acquired clonal complex 17 (CC17) Enterococcus faecium strains are genetically distinct from indigenous strains and are enriched with resistance genes and virulence genes. We identified a genomic island in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism, which may provide a competitive advantage over the indigenous E. faecium microbiota.

AB - Hospital-acquired clonal complex 17 (CC17) Enterococcus faecium strains are genetically distinct from indigenous strains and are enriched with resistance genes and virulence genes. We identified a genomic island in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism, which may provide a competitive advantage over the indigenous E. faecium microbiota.

KW - Carbohydrate Metabolism

KW - Cross Infection

KW - Enterococcus faecium

KW - Gene Order

KW - Genes, Bacterial

KW - Genomic Islands

KW - Gram-Positive Bacterial Infections

U2 - 10.1128/AEM.01378-08

DO - 10.1128/AEM.01378-08

M3 - Article

C2 - 18836023

SN - 0099-2240

VL - 74

SP - 7094

EP - 7097

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 22

ER -

Identification of a novel genomic island specific to hospital-acquired clonal complex 17 Enterococcus faecium isolates

Abstract

Keywords

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