Hypogonadism in Children with a Previous History of Cancer: Endocrine Management and Follow-Up

Hanneke M van Santen; Marry M van den Heuvel-Eibrink; Marianne D van de Wetering; W Hamish Wallace

doi:10.1159/000495943

Hypogonadism in Children with a Previous History of Cancer: Endocrine Management and Follow-Up

Hanneke M van Santen, Marry M van den Heuvel-Eibrink, Marianne D van de Wetering, W Hamish Wallace

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Abstract

Hypogonadism after treatment for childhood cancer is a recognized complication and its cause may be subdivided into primary gonadal failure and central hypogonadism. Here, we provide an overview of the risk factors for the development of hypogonadism, assessment and potential interventions and give a summary of the current recommendations for management and follow-up of hypogonadism in childhood cancer survivors.

Original language	English
Pages (from-to)	93-103
Number of pages	11
Journal	Hormone Research in Paediatrics
Volume	91
Issue number	2
Early online date	31 Jan 2019
DOIs	https://doi.org/10.1159/000495943
Publication status	Published - 1 Jun 2019

Keywords

Chemotherapy
Hypogonadism
Late effects
Premature ovarian failure

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title = "Hypogonadism in Children with a Previous History of Cancer: Endocrine Management and Follow-Up",

abstract = "Hypogonadism after treatment for childhood cancer is a recognized complication and its cause may be subdivided into primary gonadal failure and central hypogonadism. Here, we provide an overview of the risk factors for the development of hypogonadism, assessment and potential interventions and give a summary of the current recommendations for management and follow-up of hypogonadism in childhood cancer survivors.",

keywords = "Chemotherapy, Hypogonadism, Late effects, Premature ovarian failure",

author = "{van Santen}, {Hanneke M} and {van den Heuvel-Eibrink}, {Marry M} and {van de Wetering}, {Marianne D} and Wallace, {W Hamish}",

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AU - van Santen, Hanneke M

AU - van den Heuvel-Eibrink, Marry M

AU - van de Wetering, Marianne D

AU - Wallace, W Hamish

N1 - The Author(s). Published by S. Karger AG, Basel.

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AB - Hypogonadism after treatment for childhood cancer is a recognized complication and its cause may be subdivided into primary gonadal failure and central hypogonadism. Here, we provide an overview of the risk factors for the development of hypogonadism, assessment and potential interventions and give a summary of the current recommendations for management and follow-up of hypogonadism in childhood cancer survivors.

KW - Chemotherapy

KW - Hypogonadism

KW - Late effects

KW - Premature ovarian failure

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JO - Hormone Research in Paediatrics

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ER -

Hypogonadism in Children with a Previous History of Cancer: Endocrine Management and Follow-Up

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Keywords

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