Hypogonadism in Children with a Previous History of Cancer: Endocrine Management and Follow-Up

Hanneke M van Santen, Marry M van den Heuvel-Eibrink, Marianne D van de Wetering, W Hamish Wallace

Research output: Contribution to journalReview articlepeer-review

Abstract

Hypogonadism after treatment for childhood cancer is a recognized complication and its cause may be subdivided into primary gonadal failure and central hypogonadism. Here, we provide an overview of the risk factors for the development of hypogonadism, assessment and potential interventions and give a summary of the current recommendations for management and follow-up of hypogonadism in childhood cancer survivors.

Original languageEnglish
Pages (from-to)93-103
Number of pages11
JournalHormone Research in Paediatrics
Volume91
Issue number2
Early online date31 Jan 2019
DOIs
Publication statusPublished - 1 Jun 2019

Keywords

  • Chemotherapy
  • Hypogonadism
  • Late effects
  • Premature ovarian failure

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