Hurdles on the road to personalized medicine

Thomas Tursz; Rene Bernards

doi:10.1016/j.molonc.2014.08.009

Hurdles on the road to personalized medicine

Thomas Tursz
, Rene Bernards

Molecular Cancer Research

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Cancer treatment is slowly shifting from an approach in which the tissue of origin and the histology were the guiding principles for the choice of chemotherapy towards a genotype-centric approach in which the changes in the cancer genome are used to select patients for treatment with highly selective and targeted drugs. This transition has all the hallmarks of a disruptive innovation and requires major adjustments in the way that cancer is diagnosed and treated. We discuss here the hurdles on the road ahead to a more personalized treatment of cancer.

Original language	English
Pages (from-to)	935-9
Number of pages	5
Journal	Molecular Oncology
Volume	9
Issue number	5
DOIs	https://doi.org/10.1016/j.molonc.2014.08.009
Publication status	Published - 2015

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title = "Hurdles on the road to personalized medicine",

abstract = "Cancer treatment is slowly shifting from an approach in which the tissue of origin and the histology were the guiding principles for the choice of chemotherapy towards a genotype-centric approach in which the changes in the cancer genome are used to select patients for treatment with highly selective and targeted drugs. This transition has all the hallmarks of a disruptive innovation and requires major adjustments in the way that cancer is diagnosed and treated. We discuss here the hurdles on the road ahead to a more personalized treatment of cancer.",

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AB - Cancer treatment is slowly shifting from an approach in which the tissue of origin and the histology were the guiding principles for the choice of chemotherapy towards a genotype-centric approach in which the changes in the cancer genome are used to select patients for treatment with highly selective and targeted drugs. This transition has all the hallmarks of a disruptive innovation and requires major adjustments in the way that cancer is diagnosed and treated. We discuss here the hurdles on the road ahead to a more personalized treatment of cancer.

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Hurdles on the road to personalized medicine

Abstract

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