Hurdles on the road to personalized medicine

Thomas Tursz, Rene Bernards

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Cancer treatment is slowly shifting from an approach in which the tissue of origin and the histology were the guiding principles for the choice of chemotherapy towards a genotype-centric approach in which the changes in the cancer genome are used to select patients for treatment with highly selective and targeted drugs. This transition has all the hallmarks of a disruptive innovation and requires major adjustments in the way that cancer is diagnosed and treated. We discuss here the hurdles on the road ahead to a more personalized treatment of cancer.

Original languageEnglish
Pages (from-to)935-9
Number of pages5
JournalMolecular Oncology
Volume9
Issue number5
DOIs
Publication statusPublished - 2015

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