Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer

Hamzeh Kayhanian, William Cross, Suzanne E M van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Giulio Caravagna, Luis Zapata, Arne Van Hoeck, Sjors Middelkamp, Kevin Litchfield, Christopher Steele, William Waddingham, Dominic Patel, Salvatore Milite, Chen Jin, Ann-Marie Baker, Daniel C Alexander, Khurum Khan, Daniel Hochhauser, Marco NovelliBenjamin Werner, Ruben van Boxtel, Joris H Hageman, Julian R Buissant des Amorie, Josep Linares, Marjolijn J L Ligtenberg, Iris D Nagtegaal, Miangela M Laclé, Leon M G Moons, Lodewijk A A Brosens, Nischalan Pillay, Andrea Sottoriva, Trevor A Graham, Manuel Rodriguez-Justo, Kai-Keen Shiu, Hugo J G Snippert*, Marnix Jansen

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology