Holmium-166 Radioembolization in NET Patients

M Stella; Arthur Braat; Marnix Lam

doi:10.1007/978-3-030-70773-6_21

Holmium-166 Radioembolization in NET Patients

M Stella, Arthur Braat, Marnix Lam^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Abstract

Over the past decade, the application of the radionuclide holmium-166 (166Ho) as a medical isotope has been well established. Its high-energy β radiation, which can be used for a therapeutic effect, together with its γ radiation, which can be used for nuclear imaging purposes, makes it the second type of radionuclide suitable for radioembolization of unresectable liver malignancies. Furthermore, holmium-165 can be visualized by MRI because of its paramagnetic properties and by CT because of its high density. In this chapter, 166Ho radioembolization for the treatment of neuroendrocrine tumor patients will be presented. It has been demonstrated to be a feasible clinical practice and even though more evidence has to be gained, the promising results show the potentialities of 166Ho radioembolization in the treatment of metastases in the liver, commonly related to neuroendocrine tumors.

Original language	English
Title of host publication	Liver Intra-arterial PRRT with 111In-Octreotide
Subtitle of host publication	The Tumoricidal Efficacy of 111In Auger Electron Emission
Editors	Georgios S. Limouris
Place of Publication	Cham
Publisher	Springer
Chapter	20
Pages	241-250
Number of pages	10
Edition	1
ISBN (Electronic)	978-3-030-70773-6
ISBN (Print)	978-3-030-70772-9, 978-3-030-70775-0
DOIs	https://doi.org/10.1007/978-3-030-70773-6_21
Publication status	Published - May 2021

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10.1007/978-3-030-70773-6_21

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title = "Holmium-166 Radioembolization in NET Patients",

abstract = "Over the past decade, the application of the radionuclide holmium-166 (166Ho) as a medical isotope has been well established. Its high-energy β radiation, which can be used for a therapeutic effect, together with its γ radiation, which can be used for nuclear imaging purposes, makes it the second type of radionuclide suitable for radioembolization of unresectable liver malignancies. Furthermore, holmium-165 can be visualized by MRI because of its paramagnetic properties and by CT because of its high density. In this chapter, 166Ho radioembolization for the treatment of neuroendrocrine tumor patients will be presented. It has been demonstrated to be a feasible clinical practice and even though more evidence has to be gained, the promising results show the potentialities of 166Ho radioembolization in the treatment of metastases in the liver, commonly related to neuroendocrine tumors.",

author = "M Stella and Arthur Braat and Marnix Lam",

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Holmium-166 Radioembolization in NET Patients

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