HIV, HCV and HBV: A Review of Parallels and Differences

Maria C. Leoni; Andrew Ustianowski; Hamzah Farooq; Joop E. Arends

doi:10.1007/s40121-018-0210-5

HIV, HCV and HBV: A Review of Parallels and Differences

Maria C. Leoni, Andrew Ustianowski, Hamzah Farooq, Joop E. Arends^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

Elimination of the three blood-borne viruses—human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV)—as public health issues may be plausible in the near future. Spectacular advances have been made with the introduction of highly effective antiviral agents into clinical practice, and prevention strategies are available for all three infections. Effective disease control, laid out by WHO global strategies, is currently feasible for all three viruses. However, for worldwide elimination of these viruses, effective vaccines are required that are currently only available for HBV. In this review differences and parallels among HIV, HCV and HBV will be discussed with a focus on virologic and therapeutic issues, and prospects for the future of HBV will be presented.

Original language	English
Pages (from-to)	407-419
Number of pages	13
Journal	Infectious Diseases and Therapy
Volume	7
Issue number	4
DOIs	https://doi.org/10.1007/s40121-018-0210-5
Publication status	Published - 1 Dec 2018

Keywords

Antiviral therapy
Elimination
Hepatitis B virus
Hepatitis C virus
HIV virus
Vaccination

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10.1007/s40121-018-0210-5

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title = "HIV, HCV and HBV: A Review of Parallels and Differences",

abstract = "Elimination of the three blood-borne viruses—human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV)—as public health issues may be plausible in the near future. Spectacular advances have been made with the introduction of highly effective antiviral agents into clinical practice, and prevention strategies are available for all three infections. Effective disease control, laid out by WHO global strategies, is currently feasible for all three viruses. However, for worldwide elimination of these viruses, effective vaccines are required that are currently only available for HBV. In this review differences and parallels among HIV, HCV and HBV will be discussed with a focus on virologic and therapeutic issues, and prospects for the future of HBV will be presented.",

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AU - Leoni, Maria C.

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AU - Farooq, Hamzah

AU - Arends, Joop E.

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AB - Elimination of the three blood-borne viruses—human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV)—as public health issues may be plausible in the near future. Spectacular advances have been made with the introduction of highly effective antiviral agents into clinical practice, and prevention strategies are available for all three infections. Effective disease control, laid out by WHO global strategies, is currently feasible for all three viruses. However, for worldwide elimination of these viruses, effective vaccines are required that are currently only available for HBV. In this review differences and parallels among HIV, HCV and HBV will be discussed with a focus on virologic and therapeutic issues, and prospects for the future of HBV will be presented.

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KW - Elimination

KW - Hepatitis B virus

KW - Hepatitis C virus

KW - HIV virus

KW - Vaccination

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HIV, HCV and HBV: A Review of Parallels and Differences

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