High-resolution typing by integration of genome sequencing data in a large tuberculosis cluster

Anita Schürch; Kristin Kremer; Olaf Daviena; Albert Kiers; Martin J. Boeree; Roland J. Siezen; Dick Van Soolingen

doi:10.1128/JCM.00370-10

High-resolution typing by integration of genome sequencing data in a large tuberculosis cluster

Anita Schürch, Kristin Kremer, Olaf Daviena, Albert Kiers, Martin J. Boeree, Roland J. Siezen, Dick Van Soolingen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To investigate whether genome sequencing yields more useful markers than those currently used to study the epidemiology of tuberculosis, it was applied to three Mycobacterium tuberculosis isolates of the Harlingen outbreak. Our findings suggest that single nucleotide polymorphisms can be used to identify transmission chains in restriction fragment length polymorphism clusters.

Original language	English
Pages (from-to)	3403-3406
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	48
Issue number	9
DOIs	https://doi.org/10.1128/JCM.00370-10
Publication status	Published - Sept 2010
Externally published	Yes

Access to Document

10.1128/JCM.00370-10

Cite this

@article{9d94dfa3c40e4e13b0382f2db92c882e,

title = "High-resolution typing by integration of genome sequencing data in a large tuberculosis cluster",

abstract = "To investigate whether genome sequencing yields more useful markers than those currently used to study the epidemiology of tuberculosis, it was applied to three Mycobacterium tuberculosis isolates of the Harlingen outbreak. Our findings suggest that single nucleotide polymorphisms can be used to identify transmission chains in restriction fragment length polymorphism clusters.",

author = "Anita Sch{\"u}rch and Kristin Kremer and Olaf Daviena and Albert Kiers and Boeree, {Martin J.} and Siezen, {Roland J.} and {Van Soolingen}, Dick",

year = "2010",

month = sep,

doi = "10.1128/JCM.00370-10",

language = "English",

volume = "48",

pages = "3403--3406",

number = "9",

}

TY - JOUR

T1 - High-resolution typing by integration of genome sequencing data in a large tuberculosis cluster

AU - Schürch, Anita

AU - Kremer, Kristin

AU - Daviena, Olaf

AU - Kiers, Albert

AU - Boeree, Martin J.

AU - Siezen, Roland J.

AU - Van Soolingen, Dick

PY - 2010/9

Y1 - 2010/9

N2 - To investigate whether genome sequencing yields more useful markers than those currently used to study the epidemiology of tuberculosis, it was applied to three Mycobacterium tuberculosis isolates of the Harlingen outbreak. Our findings suggest that single nucleotide polymorphisms can be used to identify transmission chains in restriction fragment length polymorphism clusters.

AB - To investigate whether genome sequencing yields more useful markers than those currently used to study the epidemiology of tuberculosis, it was applied to three Mycobacterium tuberculosis isolates of the Harlingen outbreak. Our findings suggest that single nucleotide polymorphisms can be used to identify transmission chains in restriction fragment length polymorphism clusters.

UR - http://www.scopus.com/inward/record.url?scp=77956805466&partnerID=8YFLogxK

U2 - 10.1128/JCM.00370-10

DO - 10.1128/JCM.00370-10

M3 - Article

C2 - 20592143

AN - SCOPUS:77956805466

SN - 0095-1137

VL - 48

SP - 3403

EP - 3406

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 9

ER -

High-resolution typing by integration of genome sequencing data in a large tuberculosis cluster

Abstract

Access to Document

Other files and links

Fingerprint

Cite this