High-level multilineage engraftment of human cord blood cells in SCID mice

J Vormoor; T Lapidot; F Pflumio; G Risdon; B Patterson; H E Broxmeyer; J E Dick

doi:10.1089/scd.1.1993.2.215

High-level multilineage engraftment of human cord blood cells in SCID mice

J Vormoor
, T Lapidot
, F Pflumio
, G Risdon
, B Patterson
, H E Broxmeyer
, J E Dick

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Cord blood is increasingly used as an alternative to bone marrow transplantation in pediatric patients. Therefore, to study cord blood-derived hematopoiesis in vivo we are developing a xenogeneic transplantation model using immunodeficient SCID mice.

Original language	English
Pages (from-to)	215-216
Number of pages	2
Journal	Journal of hematotherapy
Volume	2
Issue number	2
DOIs	https://doi.org/10.1089/scd.1.1993.2.215
Publication status	Published - 1993
Externally published	Yes

Keywords

Animals
Bone Marrow/pathology
Colony-Forming Units Assay
Fetal Blood/cytology
Graft Survival
Hematopoietic Stem Cell Transplantation
Humans
Infant, Newborn
Mice
Mice, SCID
Radiation Chimera
Severe Combined Immunodeficiency/therapy
Transplantation, Heterologous

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10.1089/scd.1.1993.2.215

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title = "High-level multilineage engraftment of human cord blood cells in SCID mice",

abstract = "Cord blood is increasingly used as an alternative to bone marrow transplantation in pediatric patients. Therefore, to study cord blood-derived hematopoiesis in vivo we are developing a xenogeneic transplantation model using immunodeficient SCID mice.",

keywords = "Animals, Bone Marrow/pathology, Colony-Forming Units Assay, Fetal Blood/cytology, Graft Survival, Hematopoietic Stem Cell Transplantation, Humans, Infant, Newborn, Mice, Mice, SCID, Radiation Chimera, Severe Combined Immunodeficiency/therapy, Transplantation, Heterologous",

author = "J Vormoor and T Lapidot and F Pflumio and G Risdon and B Patterson and Broxmeyer, \{H E\} and Dick, \{J E\}",

year = "1993",

doi = "10.1089/scd.1.1993.2.215",

language = "English",

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pages = "215--216",

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AU - Vormoor, J

AU - Lapidot, T

AU - Pflumio, F

AU - Risdon, G

AU - Patterson, B

AU - Broxmeyer, H E

AU - Dick, J E

PY - 1993

Y1 - 1993

N2 - Cord blood is increasingly used as an alternative to bone marrow transplantation in pediatric patients. Therefore, to study cord blood-derived hematopoiesis in vivo we are developing a xenogeneic transplantation model using immunodeficient SCID mice.

AB - Cord blood is increasingly used as an alternative to bone marrow transplantation in pediatric patients. Therefore, to study cord blood-derived hematopoiesis in vivo we are developing a xenogeneic transplantation model using immunodeficient SCID mice.

KW - Animals

KW - Bone Marrow/pathology

KW - Colony-Forming Units Assay

KW - Fetal Blood/cytology

KW - Graft Survival

KW - Hematopoietic Stem Cell Transplantation

KW - Humans

KW - Infant, Newborn

KW - Mice

KW - Mice, SCID

KW - Radiation Chimera

KW - Severe Combined Immunodeficiency/therapy

KW - Transplantation, Heterologous

U2 - 10.1089/scd.1.1993.2.215

DO - 10.1089/scd.1.1993.2.215

M3 - Article

C2 - 7921977

SN - 1061-6128

VL - 2

SP - 215

EP - 216

JO - Journal of hematotherapy

JF - Journal of hematotherapy

IS - 2

ER -

High-level multilineage engraftment of human cord blood cells in SCID mice

Abstract

Keywords

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