Abstract
In three patients, two boys of 7 and 10 and a girl of 9 years old, a kidney disease was diagnosed which evolved from Schonlein-Henoch nephritis to IgA nephropathy or Berger's disease. These two kidney diseases show striking similarities in pathological and immunological respects. Several patients have been described in the literature who suffered from both clinical pictures consecutively and of families in which different members showed either one or the other disease. A remarkable finding was the persistence of an elevated IgA serum level in all three children after the Schonlein-Henoch nephritis had subsided. These cases show the importance of long-term follow up of patients who had Schonlein-Henoch nephritis, in order to diagnose late renal complications at an early stage. They also give more evidence in favour of the assumption that Schonlein-Henoch nephritis and IgA nephropathy have a common aetiology.
| Translated title of the contribution | Schonlein-Henoch purpura nephritis followed by IgA nephropathy in three children |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 316-319 |
| Number of pages | 4 |
| Journal | Nederlands Tijdschrift voor Geneeskunde |
| Volume | 140 |
| Issue number | 6 |
| Publication status | Published - 1 Jan 1996 |