TY - JOUR
T1 - Hematology patterns of migrating European eels and the role of EVEX virus
AU - Van Ginneken, V.
AU - Ballieux, B.
AU - Willemze, R.
AU - Coldenhoff, K.
AU - Lentjes, E.
AU - Antonissen, E.
AU - Haenen, O.
AU - Van Den Thillart, G.
PY - 2005/1/1
Y1 - 2005/1/1
N2 - We show that European eels infected with the rhabdovirus EVEX (Eel Virus European X) virus, developed hemorrhage and anemia during simulated migration in large swim tunnels, and died after 1000-1500 km. In contrast, virus-negative animals swam 5500 km, the estimated distance to the spawning ground of the European eel in the Sargasso Sea. Virus-positive eels showed a decline in hematocrit, which was related to the swim distance. Virus-negative eels showed a slightly increased hematocrit. Observed changes in plasma lactate dehydrogenase (LDH), total protein and aspartate aminotransferase (AAT) are indicative of a serious viral infection. Based on these observations, we conclude that eel virus infections may adversely affect the spawning migration of eels, and could be a contributing factor to the worldwide decline of eel.
AB - We show that European eels infected with the rhabdovirus EVEX (Eel Virus European X) virus, developed hemorrhage and anemia during simulated migration in large swim tunnels, and died after 1000-1500 km. In contrast, virus-negative animals swam 5500 km, the estimated distance to the spawning ground of the European eel in the Sargasso Sea. Virus-positive eels showed a decline in hematocrit, which was related to the swim distance. Virus-negative eels showed a slightly increased hematocrit. Observed changes in plasma lactate dehydrogenase (LDH), total protein and aspartate aminotransferase (AAT) are indicative of a serious viral infection. Based on these observations, we conclude that eel virus infections may adversely affect the spawning migration of eels, and could be a contributing factor to the worldwide decline of eel.
KW - Anguilla anguilla
KW - Aspartate aminotransferase
KW - Blood chemistry
KW - European eel
KW - EVEX
KW - Lactate dehydrogenase
KW - Simulated migration
KW - Total protein
KW - Virus
UR - http://www.scopus.com/inward/record.url?scp=15744394872&partnerID=8YFLogxK
U2 - 10.1016/j.cca.2005.01.011
DO - 10.1016/j.cca.2005.01.011
M3 - Article
C2 - 15792628
AN - SCOPUS:15744394872
SN - 1532-0456
VL - 140
SP - 97
EP - 102
JO - Comparative Biochemistry and Physiology - C Toxicology and Pharmacology
JF - Comparative Biochemistry and Physiology - C Toxicology and Pharmacology
IS - 1
ER -