TY - JOUR
T1 - Height Assessment in the Dutch-Origin Pediatric Cystic Fibrosis Population
AU - Woestenenk, Janna W.
AU - Gulmans, Vincent A M
AU - Van Der Ent, Cornelis K.
AU - Houwen, Roderick H J
N1 - Publisher Copyright:
© The American Society for Parenteral and Enteral Nutrition.
PY - 2017/2
Y1 - 2017/2
N2 - Background: Height evaluation is an integral part of cystic fibrosis (CF) care. Height is compared with reference values by converting it to height-for-age (HFA) z scores. However, HFA z scores do not adjust for genetic potential (ie, target height [TH]), which could result in an incorrect estimation of the height. Materials and Methods: To evaluate the magnitude of this potential problem, we assessed the agreement between HFA and HFA-adjusted-for-TH (HFA/TH) z scores in 474 Dutch children with CF. Results: In this study sample, HFA z scores were -0.07 (95% confidence interval, -0.02 to -0.12) lower than HFA/TH z scores. When HFA and HFA/TH z scores were subdivided into 4 categories (≥0, <0 and ≥-1, <-1 and ≥-2, and ≤-2), a moderate agreement was found. HFA z scores were classified lower than HFA/TH z scores in 21% of the measurements and higher in 15% of the measurements. Conclusion: In clinical routine, height evaluation based on HFA may result in underestimation or overestimation of height growth, which may induce inappropriate nutrition interventions.
AB - Background: Height evaluation is an integral part of cystic fibrosis (CF) care. Height is compared with reference values by converting it to height-for-age (HFA) z scores. However, HFA z scores do not adjust for genetic potential (ie, target height [TH]), which could result in an incorrect estimation of the height. Materials and Methods: To evaluate the magnitude of this potential problem, we assessed the agreement between HFA and HFA-adjusted-for-TH (HFA/TH) z scores in 474 Dutch children with CF. Results: In this study sample, HFA z scores were -0.07 (95% confidence interval, -0.02 to -0.12) lower than HFA/TH z scores. When HFA and HFA/TH z scores were subdivided into 4 categories (≥0, <0 and ≥-1, <-1 and ≥-2, and ≤-2), a moderate agreement was found. HFA z scores were classified lower than HFA/TH z scores in 21% of the measurements and higher in 15% of the measurements. Conclusion: In clinical routine, height evaluation based on HFA may result in underestimation or overestimation of height growth, which may induce inappropriate nutrition interventions.
KW - body height
KW - cystic fibrosis
KW - growth
KW - pediatrics
KW - target height
UR - http://www.scopus.com/inward/record.url?scp=85011596039&partnerID=8YFLogxK
U2 - 10.1177/0884533616639109
DO - 10.1177/0884533616639109
M3 - Article
C2 - 27094687
SN - 0884-5336
VL - 32
SP - 130
EP - 132
JO - Nutrition in Clinical Practice
JF - Nutrition in Clinical Practice
IS - 1
ER -