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Health related quality of life six months following surgical treatment for secondary peritonitis--using the EQ-5D questionnaire.

Translated title of the contribution: Health related quality of life six months following surgical treatment for secondary peritonitis--using the EQ-5D questionnaire.
  • K.R. Boer
  • , O. van Ruler
  • , J.B. Reitsma
  • , C.W. Mahler
  • , B.C. Opmeer
  • , E.A. Reuland
  • , H.G. Gooszen
  • , P.W. de Graaf
  • , E.J. Hesselink
  • , M.F. Gerhards
  • , E.P. Steller
  • , MA Sprangers
  • , M.A. Boermeester
  • , C.A. de Borgie
  • , J.W. van Till
  • , P.M.M. Bossuyt
  • , M.J. Schultz
  • , H. Obertop
  • , D.J. Gouma
  • , P. Tanis
  • H. Hart, M. Guijt, H.M. Oudemans, K. Bosscha, E. Ritchie, M. Vermeer, B. van Etten, C. Haazer, E. Salm, H. Rommes, R.J. Oostenbroek, L. te Velde, G. Govaert, H. Ponssen, M.K. Dinkelman, L.P.H. Leenen, E.G.J.M. Pierik, K.W.W. Lansink, K. Bakker

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

BACKGROUND: To compare health related quality of life (HR-QoL) in patients surgically treated for secondary peritonitis to that of a healthy population. And to prospectively identify factors associated with poorer (lower) HR-QoL. DESIGN: A prospective cohort of secondary peritonitis patients was mailed the EQ-5D and EQ-VAS 6-months following initial laparotomy. SETTING: Multicenter study in two academic and seven regional teaching hospitals. PATIENTS: 130 of the 155 eligible patients (84%) responded to the HR-QoL questionnaires. RESULTS: HR-QoL was significantly worse on all dimensions in peritonitis patients than in a healthy reference population. Peritonitis characteristics at initial presentation were not associated with HR-QoL at six months. A more complicated course of the disease leading to longer hospitalization times and patients with an enterostomy had a negative impact on the mobility (p = 0.02), self-care (p <0.001) and daily activities: (p = 0.01). In a multivariate analysis for the EQ-VAS every doubling of hospital stay decreases the EQ-VAS by 3.8 points (p = 0.015). Morbidity during the six-month follow-up was not found to be predictive for the EQ-5D or EQ-VAS. CONCLUSION: Six months following initial surgery, patients with secondary peritonitis report more problems in HR-QoL than a healthy reference population. Unfavorable disease characteristics at initial presentation were not predictive for poorer HR-QoL, but a more complicated course of the disease was most predictive of HR-QoL at 6 months.
Translated title of the contributionHealth related quality of life six months following surgical treatment for secondary peritonitis--using the EQ-5D questionnaire.
Original languageUndefined/Unknown
Pages (from-to)no. 35
Number of pages10
JournalHealth and Quality of Life Outcomes [E]
Volume2
Issue number5
Publication statusPublished - 2007

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