Health-related quality of life and anemia in hospitalized patients with heart failure

I H Kraai; M L A Luttik; P Johansson; R M De Jong; D J Van Veldhuisen; H L Hillege; T Jaarsma

doi:10.1016/j.ijcard.2012.05.036

Health-related quality of life and anemia in hospitalized patients with heart failure

I H Kraai, M L A Luttik, P Johansson, R M De Jong, D J Van Veldhuisen, H L Hillege, T Jaarsma

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

BACKGROUND: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.

METHODS: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.

RESULTS: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).

CONCLUSION: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.

Original language	English
Pages (from-to)	151-5
Number of pages	5
Journal	International Journal of Cardiology
Volume	161
Issue number	3
DOIs	https://doi.org/10.1016/j.ijcard.2012.05.036
Publication status	Published - 29 Nov 2012
Externally published	Yes

Keywords

Aged
Aged, 80 and over
Anemia/epidemiology
Female
Health Status
Heart Failure/epidemiology
Hospitalization/trends
Humans
Male
Middle Aged
Quality of Life/psychology

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title = "Health-related quality of life and anemia in hospitalized patients with heart failure",

abstract = "BACKGROUND: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.METHODS: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.RESULTS: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).CONCLUSION: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.",

keywords = "Aged, Aged, 80 and over, Anemia/epidemiology, Female, Health Status, Heart Failure/epidemiology, Hospitalization/trends, Humans, Male, Middle Aged, Quality of Life/psychology",

author = "Kraai, {I H} and Luttik, {M L A} and P Johansson and {De Jong}, {R M} and {Van Veldhuisen}, {D J} and Hillege, {H L} and T Jaarsma",

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doi = "10.1016/j.ijcard.2012.05.036",

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T1 - Health-related quality of life and anemia in hospitalized patients with heart failure

AU - Kraai, I H

AU - Luttik, M L A

AU - Johansson, P

AU - De Jong, R M

AU - Van Veldhuisen, D J

AU - Hillege, H L

AU - Jaarsma, T

PY - 2012/11/29

Y1 - 2012/11/29

N2 - BACKGROUND: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.METHODS: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.RESULTS: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).CONCLUSION: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.

AB - BACKGROUND: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.METHODS: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.RESULTS: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).CONCLUSION: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.

KW - Aged

KW - Aged, 80 and over

KW - Anemia/epidemiology

KW - Female

KW - Health Status

KW - Heart Failure/epidemiology

KW - Hospitalization/trends

KW - Humans

KW - Male

KW - Middle Aged

KW - Quality of Life/psychology

U2 - 10.1016/j.ijcard.2012.05.036

DO - 10.1016/j.ijcard.2012.05.036

M3 - Article

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SN - 0167-5273

VL - 161

SP - 151

EP - 155

JO - International Journal of Cardiology

JF - International Journal of Cardiology

IS - 3

ER -

Health-related quality of life and anemia in hospitalized patients with heart failure

Abstract

Keywords

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