Haemodynamic consequences of phototherapy in term infants

M. J.N.L. Benders, F. Van Bel, M. Van De Bor

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Abstract

The effect of blue-light phototherapy on cardiac output and brain and kidney perfusion was studied in 12 term infants with pulsed Doppler ultrasound. Mean (± SD) gestational age and birth weight were 39.0 (± 1.6) weeks and 3438 (± 533) g respectively. Mean (± SD) age of the infants at which phototherapy was initiated was 3.5 (± 0.8) days. Left ventricular output (LVO), mean left pulmonary artery blood flow (LPA), mean blood flow velocities of the internal carotid (CBFV) and renal (RBFV) arteries were studied in all infants prior to the onset of phototherapy, 30 min, 2 h, and 12 h after initiation of phototherapy, and before and 12-24 h after discontinuation of phototherapy. LVO decreased immediately after the onset of phototherapy. However, after 12 h, LVO returned to pre-phototherapy values. LPA increased significantly after 12 h of exposure. LPA returned to pre- phototherapy values after discontinuation of phototherapy. CBFV increased, whereas RBFV decreased significantly after 2 h of exposure. After discontinuation of phototherapy CBFV as well as RBFV values returned to pre- photo- therapy values. Conclusion: Phototherapy does affect cardiac output and organ blood flow velocity in term infants. After termination of phototherapy the effect of phototherapy disappears.

Original languageEnglish
Pages (from-to)323-328
Number of pages6
JournalEuropean Journal of Pediatrics
Volume158
Issue number4
DOIs
Publication statusPublished - 27 Apr 1999

Keywords

  • Cardiac output
  • Cerebral blood flow velocity
  • Phototherapy
  • Renal blood flow velocity
  • Term infants

Fingerprint

Dive into the research topics of 'Haemodynamic consequences of phototherapy in term infants'. Together they form a unique fingerprint.

Cite this