Guidance to develop a multidisciplinary, international, pediatric registry: a systematic review

S. Ombashi, P. A.J. van der Goes*, S. L. Versnel, R. H. Khonsari, A. E.Mink van der Molen

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Aim: The European Reference Network for craniofacial anomalies and ear, nose and throat disorders (ERN-CRANIO) aims to improve craniofacial care on a European scale. Within ERN-CRANIO, the cleft lip and palate (CL/P) work stream seeks to ameliorate health outcomes for patients with CL/P. This work stream acknowledged the need for a European wide registry for comparable outcome measures and therapy endpoints to achieve this goal. This review aimed to provide a scientific basis for the conceptualization of this registry by studying previous registry initiatives. Methods: This review performed thematic analysis on twenty-four articles through narrative synthesis. An iterative process was used to identify key-themes required for prolonged registry success. Results: Analysis of the literature resulted in twenty-one distinct headings including quantitative and qualitative data. Quantitative data including registry characteristics were visualized in a table. The analysis of qualitative data resulted in the identification of fourteen key-themes, which have been summarized and visualized in a guidance. Conclusion: This review has successfully identified key-themes required for the development of an international, multidisciplinary, pediatric registry for pan-European cleft care. The guidance provided by this review applies to the goals of ERN-CRANIO, but can be used by any initiative developing a registry.

Original languageEnglish
Article number296
JournalOrphanet Journal of Rare Diseases
Volume18
Issue number1
DOIs
Publication statusPublished - Dec 2023
Externally publishedYes

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