Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex

Sahar Abdulghani; Felipe Moretti; Peter G.J. Nikkels; Suonavy Khung-Savatovsky; Julie Hurteau-Miller; David Grynspan

doi:10.1177/1093526617697061

Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex

Sahar Abdulghani, Felipe Moretti, Peter G.J. Nikkels, Suonavy Khung-Savatovsky, Julie Hurteau-Miller, David Grynspan^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We describe a case of a pregnancy complicated by early onset asymmetric growth restriction with anhydramnios with termination occurring at 21 weeks. Fetal autopsy showed demineralization of bones and renal tubular dysgenesis. Placental pathology showed features of massive perivillous fibrin deposition and chronic histiocytic intervillositis. We review prior documentation of this association and briefly discuss potential pathogenesis.

Original language	English
Pages (from-to)	91-94
Number of pages	4
Journal	Pediatric and Developmental Pathology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1177/1093526617697061
Publication status	Published - 1 Jan 2018

Keywords

chronic intervillosistis
fetal
intrauterine growth restriction
massive perivillous fibrin
placenta
renal tubular dysgenesis

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Abdulghani, S., Moretti, F., Nikkels, P. G. J., Khung-Savatovsky, S., Hurteau-Miller, J., & Grynspan, D. (2018). Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex. Pediatric and Developmental Pathology, 21(1), 91-94. https://doi.org/10.1177/1093526617697061

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title = "Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex",

abstract = "We describe a case of a pregnancy complicated by early onset asymmetric growth restriction with anhydramnios with termination occurring at 21 weeks. Fetal autopsy showed demineralization of bones and renal tubular dysgenesis. Placental pathology showed features of massive perivillous fibrin deposition and chronic histiocytic intervillositis. We review prior documentation of this association and briefly discuss potential pathogenesis.",

keywords = "chronic intervillosistis, fetal, intrauterine growth restriction, massive perivillous fibrin, placenta, renal tubular dysgenesis",

author = "Sahar Abdulghani and Felipe Moretti and Nikkels, {Peter G.J.} and Suonavy Khung-Savatovsky and Julie Hurteau-Miller and David Grynspan",

year = "2018",

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doi = "10.1177/1093526617697061",

language = "English",

volume = "21",

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Abdulghani, S, Moretti, F, Nikkels, PGJ, Khung-Savatovsky, S, Hurteau-Miller, J & Grynspan, D 2018, 'Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex', Pediatric and Developmental Pathology, vol. 21, no. 1, pp. 91-94. https://doi.org/10.1177/1093526617697061

Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex. / Abdulghani, Sahar; Moretti, Felipe; Nikkels, Peter G.J. et al.
In: Pediatric and Developmental Pathology, Vol. 21, No. 1, 01.01.2018, p. 91-94.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex

AU - Abdulghani, Sahar

AU - Moretti, Felipe

AU - Nikkels, Peter G.J.

AU - Khung-Savatovsky, Suonavy

AU - Hurteau-Miller, Julie

AU - Grynspan, David

PY - 2018/1/1

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N2 - We describe a case of a pregnancy complicated by early onset asymmetric growth restriction with anhydramnios with termination occurring at 21 weeks. Fetal autopsy showed demineralization of bones and renal tubular dysgenesis. Placental pathology showed features of massive perivillous fibrin deposition and chronic histiocytic intervillositis. We review prior documentation of this association and briefly discuss potential pathogenesis.

AB - We describe a case of a pregnancy complicated by early onset asymmetric growth restriction with anhydramnios with termination occurring at 21 weeks. Fetal autopsy showed demineralization of bones and renal tubular dysgenesis. Placental pathology showed features of massive perivillous fibrin deposition and chronic histiocytic intervillositis. We review prior documentation of this association and briefly discuss potential pathogenesis.

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KW - fetal

KW - intrauterine growth restriction

KW - massive perivillous fibrin

KW - placenta

KW - renal tubular dysgenesis

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IS - 1

ER -

Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex

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Keywords

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