Going into surgery: Risk factors for hypertrophic scarring

Lisolette Butzelaar; Ezgi A. Soykan; Francisca Galindo Garre; Robert H. J. Beelen; Magda M. Ulrich; Frank B. Niessen; AB Mink van der Molen

doi:10.1111/wrr.12302

Going into surgery: Risk factors for hypertrophic scarring

Lisolette Butzelaar, Ezgi A. Soykan, Francisca Galindo Garre, Robert H. J. Beelen, Magda M. Ulrich, Frank B. Niessen, AB Mink van der Molen

Department of Plastic and Reconstructive Surgery

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The aim of this study was to examine the association between possible risk factors for excessive scarring and the formation of hypertrophic scars (HTS). Hypertrophic skin scarring remains a difficult problem in medicine and can cause considerable morbidity. Nevertheless, few extensive prospective studies have been conducted which assess risk factors in relation to HTS formation. Therefore, a prospective observational study was performed. Patients who had elective cardiothoracic surgery were followed for the duration of 1 year and information was collected about a variety of possible risk factors in these patients. The associations between the risk factors and the development of HTSs were investigated. Body mass index, ethnic background, and scar related factors are positively associated with HTS formation. Antihypertensive therapeutics and factors influencing erythropoiesis are negatively associated with HTS formation.

Original language	English
Pages (from-to)	531-537
Journal	Wound Repair and Regeneration
Volume	23
Issue number	4
DOIs	https://doi.org/10.1111/wrr.12302
Publication status	Published - 2015

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10.1111/wrr.12302

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title = "Going into surgery: Risk factors for hypertrophic scarring",

abstract = "The aim of this study was to examine the association between possible risk factors for excessive scarring and the formation of hypertrophic scars (HTS). Hypertrophic skin scarring remains a difficult problem in medicine and can cause considerable morbidity. Nevertheless, few extensive prospective studies have been conducted which assess risk factors in relation to HTS formation. Therefore, a prospective observational study was performed. Patients who had elective cardiothoracic surgery were followed for the duration of 1 year and information was collected about a variety of possible risk factors in these patients. The associations between the risk factors and the development of HTSs were investigated. Body mass index, ethnic background, and scar related factors are positively associated with HTS formation. Antihypertensive therapeutics and factors influencing erythropoiesis are negatively associated with HTS formation.",

author = "Lisolette Butzelaar and Soykan, {Ezgi A.} and Garre, {Francisca Galindo} and Beelen, {Robert H. J.} and Ulrich, {Magda M.} and Niessen, {Frank B.} and {Mink van der Molen}, AB",

year = "2015",

doi = "10.1111/wrr.12302",

language = "English",

volume = "23",

pages = "531--537",

journal = "Wound Repair and Regeneration",

issn = "1067-1927",

publisher = "Wiley-Blackwell",

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TY - JOUR

T1 - Going into surgery: Risk factors for hypertrophic scarring

AU - Butzelaar, Lisolette

AU - Soykan, Ezgi A.

AU - Garre, Francisca Galindo

AU - Beelen, Robert H. J.

AU - Ulrich, Magda M.

AU - Niessen, Frank B.

AU - Mink van der Molen, AB

PY - 2015

Y1 - 2015

N2 - The aim of this study was to examine the association between possible risk factors for excessive scarring and the formation of hypertrophic scars (HTS). Hypertrophic skin scarring remains a difficult problem in medicine and can cause considerable morbidity. Nevertheless, few extensive prospective studies have been conducted which assess risk factors in relation to HTS formation. Therefore, a prospective observational study was performed. Patients who had elective cardiothoracic surgery were followed for the duration of 1 year and information was collected about a variety of possible risk factors in these patients. The associations between the risk factors and the development of HTSs were investigated. Body mass index, ethnic background, and scar related factors are positively associated with HTS formation. Antihypertensive therapeutics and factors influencing erythropoiesis are negatively associated with HTS formation.

AB - The aim of this study was to examine the association between possible risk factors for excessive scarring and the formation of hypertrophic scars (HTS). Hypertrophic skin scarring remains a difficult problem in medicine and can cause considerable morbidity. Nevertheless, few extensive prospective studies have been conducted which assess risk factors in relation to HTS formation. Therefore, a prospective observational study was performed. Patients who had elective cardiothoracic surgery were followed for the duration of 1 year and information was collected about a variety of possible risk factors in these patients. The associations between the risk factors and the development of HTSs were investigated. Body mass index, ethnic background, and scar related factors are positively associated with HTS formation. Antihypertensive therapeutics and factors influencing erythropoiesis are negatively associated with HTS formation.

U2 - 10.1111/wrr.12302

DO - 10.1111/wrr.12302

M3 - Article

C2 - 25857804

SN - 1067-1927

VL - 23

SP - 531

EP - 537

JO - Wound Repair and Regeneration

JF - Wound Repair and Regeneration

IS - 4

ER -

Going into surgery: Risk factors for hypertrophic scarring

Abstract

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