Glucocorticoid-induced osteoporosis: An overview

Natalia O. Kuchuk; Jos N. Hoes; Johannes W.J. Bijlsma; Johannes W.G. Jacobs

doi:10.2217/ijr.14.24

Glucocorticoid-induced osteoporosis: An overview

Natalia O. Kuchuk, Jos N. Hoes, Johannes W.J. Bijlsma, Johannes W.G. Jacobs^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Abstract

Glucocorticoid-induced osteoporosis (GIOP) is one of the most serious adverse effects of glucocorticoids. Despite guidelines on the management of GIOP, effective medications and fracture outpatient clinics, this condition remains under-recognized and under-treated. This review covers recent insights into mechanisms involved in GIOP, monitoring for adverse effects of glucocorticoids on bone and prevention and treatment of GIOP. Recent guidelines on GIOP are discussed and a research agenda is proposed.

Original language	English
Pages (from-to)	311-326
Number of pages	16
Journal	International Journal of Clinical Rheumatology
Volume	9
Issue number	3
DOIs	https://doi.org/10.2217/ijr.14.24
Publication status	Published - 1 Jan 2014

Keywords

bisphosphonates
bone mineral density
glucocorticoids
monitoring
osteoporosis
therapy

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10.2217/ijr.14.24

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title = "Glucocorticoid-induced osteoporosis: An overview",

abstract = "Glucocorticoid-induced osteoporosis (GIOP) is one of the most serious adverse effects of glucocorticoids. Despite guidelines on the management of GIOP, effective medications and fracture outpatient clinics, this condition remains under-recognized and under-treated. This review covers recent insights into mechanisms involved in GIOP, monitoring for adverse effects of glucocorticoids on bone and prevention and treatment of GIOP. Recent guidelines on GIOP are discussed and a research agenda is proposed.",

keywords = "bisphosphonates, bone mineral density, glucocorticoids, monitoring, osteoporosis, therapy",

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AU - Kuchuk, Natalia O.

AU - Hoes, Jos N.

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AU - Jacobs, Johannes W.G.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Glucocorticoid-induced osteoporosis (GIOP) is one of the most serious adverse effects of glucocorticoids. Despite guidelines on the management of GIOP, effective medications and fracture outpatient clinics, this condition remains under-recognized and under-treated. This review covers recent insights into mechanisms involved in GIOP, monitoring for adverse effects of glucocorticoids on bone and prevention and treatment of GIOP. Recent guidelines on GIOP are discussed and a research agenda is proposed.

AB - Glucocorticoid-induced osteoporosis (GIOP) is one of the most serious adverse effects of glucocorticoids. Despite guidelines on the management of GIOP, effective medications and fracture outpatient clinics, this condition remains under-recognized and under-treated. This review covers recent insights into mechanisms involved in GIOP, monitoring for adverse effects of glucocorticoids on bone and prevention and treatment of GIOP. Recent guidelines on GIOP are discussed and a research agenda is proposed.

KW - bisphosphonates

KW - bone mineral density

KW - glucocorticoids

KW - monitoring

KW - osteoporosis

KW - therapy

UR - https://www.scopus.com/pages/publications/84905446755

U2 - 10.2217/ijr.14.24

DO - 10.2217/ijr.14.24

M3 - Review article

AN - SCOPUS:84905446755

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SP - 311

EP - 326

JO - International Journal of Clinical Rheumatology

JF - International Journal of Clinical Rheumatology

IS - 3

ER -

Glucocorticoid-induced osteoporosis: An overview

Abstract

Keywords

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