Glanzmann thrombasthenia complicated by frequent myeloproliferative neoplasm-related thromboembolism: thrombosis occurring regardless of αIIbβIII integrin deficiency

Roger E.G. Schutgens*, Rolf T. Urbanus

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

10 Downloads (Pure)

Abstract

A patient with Glanzmann Thrombasthenia developed recurrent venous thrombosis with a JAK2 positive myeloproliferative neoplasm. This indicates that the platelet aIIbβIII integrin has no role in venous thrombosis. We discuss the other potential mechanisms that are involved. In addition, we describe the successful use of dabigatran in this patient.

Original languageEnglish
Article numbere04757
Pages (from-to)1-3
JournalClinical case reports
Volume9
Issue number9
DOIs
Publication statusPublished - Sept 2021

Keywords

  • dabigatran
  • Glanzmann thrombasthenia
  • myeloproliferative neoplasm
  • platelet
  • venous thrombosis
  • αIIbβIII integrin
  • alpha IIb beta III integrin

Fingerprint

Dive into the research topics of 'Glanzmann thrombasthenia complicated by frequent myeloproliferative neoplasm-related thromboembolism: thrombosis occurring regardless of αIIbβIII integrin deficiency'. Together they form a unique fingerprint.

Cite this