GENTAMICINE-HUIDZALF: 200 KILO TE VEEL

N. H.M. Renders; J. A.J.W. Kluytmans; E. Stolz; H. A. Verbrugh

GENTAMICINE-HUIDZALF: 200 KILO TE VEEL

Translated title of the contribution: Resistance to antibiotics due to use of obsolete gentamicin skin ointment

N. H.M. Renders^*
, J. A.J.W. Kluytmans
, E. Stolz
, H. A. Verbrugh

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Scopus)

Abstract

In a 75-year-old woman, with diabetic mellitus type II, bacteriological examination of a foot infection revealed a Staphylococcus aureus resistant to aminoglycosides. From a different ulcer on the same foot of genotypically identical but non-resistant bacterial strain was cultured. The patient had been treated with gentamicin ointment. According to the literature and to the Central Pharmaceutical Committee in the Netherlands there is no indication for topical use of gentamicin or other aminoglycosides. Moreover, such use may lead to antibiotic resistant bacteria. In spite of this, in the period from March 1992 to March 1993, 200 kg of the ointment was distributed in the Netherlands.

Translated title of the contribution	Resistance to antibiotics due to use of obsolete gentamicin skin ointment
Original language	Dutch
Pages (from-to)	2314-2316
Number of pages	3
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	139
Issue number	45
Publication status	Published - 1995
Externally published	Yes

Cite this

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title = "GENTAMICINE-HUIDZALF: 200 KILO TE VEEL",

abstract = "In a 75-year-old woman, with diabetic mellitus type II, bacteriological examination of a foot infection revealed a Staphylococcus aureus resistant to aminoglycosides. From a different ulcer on the same foot of genotypically identical but non-resistant bacterial strain was cultured. The patient had been treated with gentamicin ointment. According to the literature and to the Central Pharmaceutical Committee in the Netherlands there is no indication for topical use of gentamicin or other aminoglycosides. Moreover, such use may lead to antibiotic resistant bacteria. In spite of this, in the period from March 1992 to March 1993, 200 kg of the ointment was distributed in the Netherlands.",

author = "Renders, \{N. H.M.\} and Kluytmans, \{J. A.J.W.\} and E. Stolz and Verbrugh, \{H. A.\}",

year = "1995",

language = "Dutch",

volume = "139",

pages = "2314--2316",

journal = "Nederlands Tijdschrift voor Geneeskunde",

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TY - JOUR

T1 - GENTAMICINE-HUIDZALF

T2 - 200 KILO TE VEEL

AU - Renders, N. H.M.

AU - Kluytmans, J. A.J.W.

AU - Stolz, E.

AU - Verbrugh, H. A.

PY - 1995

Y1 - 1995

N2 - In a 75-year-old woman, with diabetic mellitus type II, bacteriological examination of a foot infection revealed a Staphylococcus aureus resistant to aminoglycosides. From a different ulcer on the same foot of genotypically identical but non-resistant bacterial strain was cultured. The patient had been treated with gentamicin ointment. According to the literature and to the Central Pharmaceutical Committee in the Netherlands there is no indication for topical use of gentamicin or other aminoglycosides. Moreover, such use may lead to antibiotic resistant bacteria. In spite of this, in the period from March 1992 to March 1993, 200 kg of the ointment was distributed in the Netherlands.

AB - In a 75-year-old woman, with diabetic mellitus type II, bacteriological examination of a foot infection revealed a Staphylococcus aureus resistant to aminoglycosides. From a different ulcer on the same foot of genotypically identical but non-resistant bacterial strain was cultured. The patient had been treated with gentamicin ointment. According to the literature and to the Central Pharmaceutical Committee in the Netherlands there is no indication for topical use of gentamicin or other aminoglycosides. Moreover, such use may lead to antibiotic resistant bacteria. In spite of this, in the period from March 1992 to March 1993, 200 kg of the ointment was distributed in the Netherlands.

UR - https://www.scopus.com/pages/publications/0028892270

M3 - Article

C2 - 7501065

AN - SCOPUS:0028892270

SN - 0028-2162

VL - 139

SP - 2314

EP - 2316

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

IS - 45

ER -

GENTAMICINE-HUIDZALF: 200 KILO TE VEEL

Abstract

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