Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies

D. Pons; S. Trompet; A.J.M. de Craen; P.E. Thijssen; P.H. Quax; M.R. de Vries; R.J. Wierda; P.J. van den Elsen; P.S. Monraats; M.M. Ewing; B.T. Heijmans; P.E. Slagboom; A.H. Zwinderman; P.A.F.M. Doevendans; R.A. Tio; R.J. de Winter; M.P. de Maat; O.A. Iakoubova; N. Sattar; J. Shepherd; R.G.J. Westendorp; J.W. Jukema

doi:10.1136/hrt.2010.199927

Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies

D. Pons
, S. Trompet
, A.J.M. de Craen
, P.E. Thijssen
, P.H. Quax
, M.R. de Vries
, R.J. Wierda
, P.J. van den Elsen
, P.S. Monraats
, M.M. Ewing
, B.T. Heijmans
, P.E. Slagboom
, A.H. Zwinderman
, P.A.F.M. Doevendans
, R.A. Tio
, R.J. de Winter
, M.P. de Maat
, O.A. Iakoubova
, N. Sattar
, J. Shepherd

R.G.J. Westendorp, J.W. Jukema

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	143-50
Number of pages	8
Journal	Heart
Volume	97
Issue number	2
DOIs	https://doi.org/10.1136/hrt.2010.199927
Publication status	Published - 2011

Access to Document

10.1136/hrt.2010.199927

http://www.ncbi.nlm.nih.gov/pubmed/21062767

Cite this

Pons, D., Trompet, S., de Craen, A. J. M., Thijssen, P. E., Quax, P. H., de Vries, M. R., Wierda, R. J., van den Elsen, P. J., Monraats, P. S., Ewing, M. M., Heijmans, B. T., Slagboom, P. E., Zwinderman, A. H., Doevendans, P. A. F. M., Tio, R. A., de Winter, R. J., de Maat, M. P., Iakoubova, O. A., Sattar, N., ... Jukema, J. W. (2011). Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies. Heart, 97(2), 143-50. https://doi.org/10.1136/hrt.2010.199927

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title = "Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies",

author = "D. Pons and S. Trompet and \{de Craen\}, A.J.M. and P.E. Thijssen and P.H. Quax and \{de Vries\}, M.R. and R.J. Wierda and \{van den Elsen\}, P.J. and P.S. Monraats and M.M. Ewing and B.T. Heijmans and P.E. Slagboom and A.H. Zwinderman and P.A.F.M. Doevendans and R.A. Tio and \{de Winter\}, R.J. and \{de Maat\}, M.P. and O.A. Iakoubova and N. Sattar and J. Shepherd and R.G.J. Westendorp and J.W. Jukema",

year = "2011",

doi = "10.1136/hrt.2010.199927",

language = "English",

volume = "97",

pages = "143--50",

journal = "Heart",

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}

Pons, D, Trompet, S, de Craen, AJM, Thijssen, PE, Quax, PH, de Vries, MR, Wierda, RJ, van den Elsen, PJ, Monraats, PS, Ewing, MM, Heijmans, BT, Slagboom, PE, Zwinderman, AH, Doevendans, PAFM, Tio, RA, de Winter, RJ, de Maat, MP, Iakoubova, OA, Sattar, N, Shepherd, J, Westendorp, RGJ & Jukema, JW 2011, 'Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies', Heart, vol. 97, no. 2, pp. 143-50. https://doi.org/10.1136/hrt.2010.199927

TY - JOUR

T1 - Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies

AU - Pons, D.

AU - Trompet, S.

AU - de Craen, A.J.M.

AU - Thijssen, P.E.

AU - Quax, P.H.

AU - de Vries, M.R.

AU - Wierda, R.J.

AU - van den Elsen, P.J.

AU - Monraats, P.S.

AU - Ewing, M.M.

AU - Heijmans, B.T.

AU - Slagboom, P.E.

AU - Zwinderman, A.H.

AU - Doevendans, P.A.F.M.

AU - Tio, R.A.

AU - de Winter, R.J.

AU - de Maat, M.P.

AU - Iakoubova, O.A.

AU - Sattar, N.

AU - Shepherd, J.

AU - Westendorp, R.G.J.

AU - Jukema, J.W.

PY - 2011

Y1 - 2011

U2 - 10.1136/hrt.2010.199927

DO - 10.1136/hrt.2010.199927

M3 - Article

C2 - 21062767

SN - 1355-6037

VL - 97

SP - 143

EP - 150

JO - Heart

JF - Heart

IS - 2

ER -