General practitioner-led vs surgeon-led colon cancer survivorship care: a randomized clinical trial

Julien A M Vos; Laura A M Duineveld; Thijs Wieldraaijer; Jan Wind; Wim B Busschers; Edanur Sert; Irma M Verdonck-de Leeuw; Henk C P M van Weert; Kristel M van Asselt

doi:10.1093/jncics/pkaf052

General practitioner-led vs surgeon-led colon cancer survivorship care: a randomized clinical trial

Julien A M Vos^*
, Laura A M Duineveld
, Thijs Wieldraaijer
, Jan Wind
, Wim B Busschers
, Edanur Sert
, Irma M Verdonck-de Leeuw
, Henk C P M van Weert
, Kristel M van Asselt

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

The randomized controlled I CARE (Improving Care After colon canceR treatment in the Netherlands) trial evaluated the impact of general practitioner-led vs surgeon-led survivorship care on quality of life (QoL) in colorectal cancer survivors, alongside the effect of the eHealth application Oncokompas. The trial was conducted in 8 hospitals and 225 general practices across the Netherlands, including 303 patients who underwent surgery for stage I-III colon cancer or rectosigmoid carcinoma. Patients were randomly assigned into 4 groups: surgeon-led care, surgeon-led care with Oncokompas, general practitioner-led care, and general practitioner-led care with Oncokompas. QoL was assessed at multiple time points over 60 months. At 60 months, no clinically relevant differences in QoL were found between general practitioner-led and surgeon-led care (difference in summary score = -0.5, 95% CI = -1.6 to 0.5) or with Oncokompas (difference = 0.8, 95% CI = 0.0 to 1.6). In conclusion, neither general practitioner involvement nor access to Oncokompas led to clinically relevant improvements in long-term QoL. Survivorship care can be tailored to preferences. Netherlands Trial Register; NTR4860.

Original language	English
Article number	pkaf052
Journal	JNCI cancer spectrum
Volume	9
Issue number	3
DOIs	https://doi.org/10.1093/jncics/pkaf052
Publication status	Published - Jun 2025

Keywords

Aged
Aged, 80 and over
Cancer Survivors/psychology
Colonic Neoplasms/surgery
Female
General Practitioners
Humans
Male
Middle Aged
Netherlands
Quality of Life
Surgeons
Survivorship
Telemedicine

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General practitioner–led vs surgeon-led colon cancer survivorship care: a randomized clinical trial Final published version, 887 KBLicence: CC BY-NC

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title = "General practitioner-led vs surgeon-led colon cancer survivorship care: a randomized clinical trial",

abstract = "The randomized controlled I CARE (Improving Care After colon canceR treatment in the Netherlands) trial evaluated the impact of general practitioner-led vs surgeon-led survivorship care on quality of life (QoL) in colorectal cancer survivors, alongside the effect of the eHealth application Oncokompas. The trial was conducted in 8 hospitals and 225 general practices across the Netherlands, including 303 patients who underwent surgery for stage I-III colon cancer or rectosigmoid carcinoma. Patients were randomly assigned into 4 groups: surgeon-led care, surgeon-led care with Oncokompas, general practitioner-led care, and general practitioner-led care with Oncokompas. QoL was assessed at multiple time points over 60 months. At 60 months, no clinically relevant differences in QoL were found between general practitioner-led and surgeon-led care (difference in summary score = -0.5, 95\% CI = -1.6 to 0.5) or with Oncokompas (difference = 0.8, 95\% CI = 0.0 to 1.6). In conclusion, neither general practitioner involvement nor access to Oncokompas led to clinically relevant improvements in long-term QoL. Survivorship care can be tailored to preferences. Netherlands Trial Register; NTR4860.",

keywords = "Aged, Aged, 80 and over, Cancer Survivors/psychology, Colonic Neoplasms/surgery, Female, General Practitioners, Humans, Male, Middle Aged, Netherlands, Quality of Life, Surgeons, Survivorship, Telemedicine",

author = "Vos, \{Julien A M\} and Duineveld, \{Laura A M\} and Thijs Wieldraaijer and Jan Wind and Busschers, \{Wim B\} and Edanur Sert and \{Verdonck-de Leeuw\}, \{Irma M\} and \{van Weert\}, \{Henk C P M\} and \{van Asselt\}, \{Kristel M\}",

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doi = "10.1093/jncics/pkaf052",

language = "English",

volume = "9",

journal = "JNCI cancer spectrum",

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AU - Wind, Jan

AU - Busschers, Wim B

AU - Sert, Edanur

AU - Verdonck-de Leeuw, Irma M

AU - van Weert, Henk C P M

AU - van Asselt, Kristel M

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KW - Male

KW - Middle Aged

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General practitioner-led vs surgeon-led colon cancer survivorship care: a randomized clinical trial

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