From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells

Saskia J.E. Suijkerbuijk; Jacco van Rheenen

doi:10.1016/j.ydbio.2017.04.015

From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells

Saskia J.E. Suijkerbuijk, Jacco van Rheenen^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

Homeostasis of tissues is tightly regulated at the cellular, tissue and organismal level. Interestingly, tumor cells have found ways to hijack many of these physiological processes at all the different levels. Here we review how intravital microscopy techniques have provided new insights into our understanding of tissue homeostasis and cancer progression. In addition, we highlight the different strategies that tumor cells have adopted to use these physiological processes for their own benefit. We describe how visualization of these dynamic processes in living mice has broadened to our view on cancer initiation and progression.

Original language	English
Pages (from-to)	328-337
Number of pages	10
Journal	Developmental Biology
Volume	428
Issue number	2
DOIs	https://doi.org/10.1016/j.ydbio.2017.04.015
Publication status	Published - 15 Aug 2017

Keywords

Adult Stem Cells
Animals
Cell Communication
Cell Movement
Disease Progression
Humans
Inflammation
Intravital Microscopy
Journal Article
Neoplasms
Neoplastic Stem Cells
Neovascularization, Pathologic
Research Support, Non-U.S. Gov't
Review
Stem Cell Niche
Tumor Microenvironment
Wound Healing

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10.1016/j.ydbio.2017.04.015

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title = "From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells",

abstract = "Homeostasis of tissues is tightly regulated at the cellular, tissue and organismal level. Interestingly, tumor cells have found ways to hijack many of these physiological processes at all the different levels. Here we review how intravital microscopy techniques have provided new insights into our understanding of tissue homeostasis and cancer progression. In addition, we highlight the different strategies that tumor cells have adopted to use these physiological processes for their own benefit. We describe how visualization of these dynamic processes in living mice has broadened to our view on cancer initiation and progression.",

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author = "Suijkerbuijk, {Saskia J.E.} and {van Rheenen}, Jacco",

note = "Publisher Copyright: {\textcopyright} 2017 The Authors",

year = "2017",

month = aug,

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doi = "10.1016/j.ydbio.2017.04.015",

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T2 - Intravital imaging of the hijack of physiological processes by cancer cells

AU - Suijkerbuijk, Saskia J.E.

AU - van Rheenen, Jacco

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N2 - Homeostasis of tissues is tightly regulated at the cellular, tissue and organismal level. Interestingly, tumor cells have found ways to hijack many of these physiological processes at all the different levels. Here we review how intravital microscopy techniques have provided new insights into our understanding of tissue homeostasis and cancer progression. In addition, we highlight the different strategies that tumor cells have adopted to use these physiological processes for their own benefit. We describe how visualization of these dynamic processes in living mice has broadened to our view on cancer initiation and progression.

AB - Homeostasis of tissues is tightly regulated at the cellular, tissue and organismal level. Interestingly, tumor cells have found ways to hijack many of these physiological processes at all the different levels. Here we review how intravital microscopy techniques have provided new insights into our understanding of tissue homeostasis and cancer progression. In addition, we highlight the different strategies that tumor cells have adopted to use these physiological processes for their own benefit. We describe how visualization of these dynamic processes in living mice has broadened to our view on cancer initiation and progression.

KW - Adult Stem Cells

KW - Animals

KW - Cell Communication

KW - Cell Movement

KW - Disease Progression

KW - Humans

KW - Inflammation

KW - Intravital Microscopy

KW - Journal Article

KW - Neoplasms

KW - Neoplastic Stem Cells

KW - Neovascularization, Pathologic

KW - Research Support, Non-U.S. Gov't

KW - Review

KW - Stem Cell Niche

KW - Tumor Microenvironment

KW - Wound Healing

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DO - 10.1016/j.ydbio.2017.04.015

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AN - SCOPUS:85018434957

SN - 0012-1606

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SP - 328

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JO - Developmental Biology

JF - Developmental Biology

IS - 2

ER -

From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells

Abstract

Keywords

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