Focus on risk factors for cardiometabolic disease in cerebral palsy: Toward a Core Set of Outcome Measurement Instruments

Joyce L. Benner*, Patrick G. McPhee, Jan Willem Gorter, Edward A. Hurvitz, Mark D. Peterson, Joyce Obeid, Marilyn Wright, Astrid C.J. Balemans, Olaf Verschuren, Rita H.J. van den Berg-Emons, Wilma M.A. van der Slot, Marij E. Roebroeck

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Objective: To identify existing outcome measurement instruments (OMIs) assessing risk factors for cardiometabolic disease in adolescents and adults with cerebral palsy (CP) reported on in the literature or used in the field. Data Sources: The COnsensus-based Standards for the selection of health Measurement Instruments database of systematic reviews and 4 electronic databases (Embase, MEDLINE/Ovid, MEDLINE/Pubmed, PsychINFO) were searched up to June 19, 2017, that yielded 2594 articles. Experts in the field were consulted to identify any additional OMIs. Study Selection: Two reviewers independently applied inclusion criteria to select eligible studies using or evaluating measurement properties of OMIs assessing 1 of 8 outcomes: cardiorespiratory endurance, body size, body composition, physical behavior, sleep, nutrition, blood pressure, and blood lipids and glucose. Studies with an experimental or observational design including ≥10 adolescents or adults with CP were included. Data Extraction: One reviewer extracted data that were summarized for study and sample characteristics, outcomes, OMIs used, and if applicable data on measurement properties. Two reviewers rated the methodological quality and the quality of the OMIs. Feasibility for clinical practice and research was rated by experts in the field. Data Synthesis: Ninety OMIs were identified from 56 included articles and by the experts. Seventy OMIs pertained to cardiorespiratory endurance, body size, body composition, and physical behavior, whereas only 5 were identified for sleep and nutrition. Overall synthesis revealed that there is moderate to poor evidence for good quality of OMIs in this population. Based on feasibility for clinical practice, experts agreed on a single OMI per outcome (and 2 for cardiorespiratory endurance) to be included in a core set. Conclusion: Despite the range of available OMIs to assess risk factors for cardiometabolic disease in adolescents and adults with CP, evidence of good quality is often lacking. Nonetheless, a preliminary core set of 9 OMIs was systematically developed.

Original languageEnglish
Pages (from-to)2389-2398
Number of pages10
JournalArchives of Physical Medicine and Rehabilitation
Volume100
Issue number12
Early online date22 May 2019
DOIs
Publication statusPublished - Dec 2019

Keywords

  • Cerebral palsy
  • Rehabilitation
  • Risk factors
  • Systematic review

Fingerprint

Dive into the research topics of 'Focus on risk factors for cardiometabolic disease in cerebral palsy: Toward a Core Set of Outcome Measurement Instruments'. Together they form a unique fingerprint.

Cite this