@article{5987d53742d64d34aefce5a9bd26f30f,
title = "Feasibility and safety of single-fraction sub-ablative radiotherapy with systemic therapy in colorectal cancer patients with ≤ 10 metastases: A multicenter pilot study (NCT05375708)",
abstract = "Colorectal cancer patients with ≤10 unresectable metastases were treated with single-fraction sub-ablative radiotherapy in addition to standard of care systemic therapy in a single-arm, open-label, multicenter, pilot study (SIRIUS) to assess feasibility and safety. Results indicate that radiotherapy combined with systemic therapy is feasible and safe in this population.",
keywords = "Oligometastases, phase I, SBRT, Single fraction, Systemic therapy",
author = "K. Zwart and Braat, \{M. N.G.J.A.\} and \{van der Baan\}, \{F. H.\} and May, \{A. M.\} and Roodhart, \{J. M.L.\} and D. Al-Toma and Otten, \{J. M.M.B.\} and M. Los and T. Oostergo and Fijneman, \{R. J.A.\} and \{van Dodewaard-de Jong\}, \{J. M.\} and Punt, \{C. J.A.\} and G. Meijer and Lagendijk, \{J. J.W.\} and M. Koopman and M. Intven and Bol, \{G. M.\}",
note = "Publisher Copyright: {\textcopyright} 2024 The Authors",
year = "2024",
month = nov,
doi = "10.1016/j.ctro.2024.100874",
language = "English",
volume = "49",
pages = "1--5",
journal = "Clinical and translational radiation oncology",
issn = "2405-6308",
publisher = "Elsevier Ireland Ltd",
}