Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

María T Illnait-Zaragozí; Lilia M Ortega-Gonzalez; Ferry Hagen; Gerardo F Martínez-Machin; Jacques F Meis

doi:10.1016/j.mmcr.2013.02.001

Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

María T Illnait-Zaragozí
, Lilia M Ortega-Gonzalez
, Ferry Hagen
, Gerardo F Martínez-Machin
, Jacques F Meis^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.

Original language	English
Pages (from-to)	48-51
Number of pages	4
Journal	Medical Mycology Case Reports
Volume	2
DOIs	https://doi.org/10.1016/j.mmcr.2013.02.001
Publication status	Published - 9 Feb 2013
Externally published	Yes

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title = "Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient",

abstract = "We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.",

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AU - Illnait-Zaragozí, María T

AU - Ortega-Gonzalez, Lilia M

AU - Hagen, Ferry

AU - Martínez-Machin, Gerardo F

AU - Meis, Jacques F

PY - 2013/2/9

Y1 - 2013/2/9

N2 - We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.

AB - We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.

U2 - 10.1016/j.mmcr.2013.02.001

DO - 10.1016/j.mmcr.2013.02.001

M3 - Article

C2 - 24432215

SN - 2211-7539

VL - 2

SP - 48

EP - 51

JO - Medical Mycology Case Reports

JF - Medical Mycology Case Reports

ER -

Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

Abstract

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