Fast-Proliferating Adipose Tissue Mesenchymal-Stromal-Like Cells for Therapy

E. Aguilar; J. Rodriguez Bago; C. Soler-Botija; M. Alieva; M.A. Rigola; C. Fuster; O.F. Vila; N. Rubio; J. Blanco

Fast-Proliferating Adipose Tissue Mesenchymal-Stromal-Like Cells for Therapy

Translated title of the contribution: Fast-Proliferating Adipose Tissue Mesenchymal-Stromal-Like Cells for Therapy

E. Aguilar
, J. Rodriguez Bago
, C. Soler-Botija
, M. Alieva
, M.A. Rigola
, C. Fuster
, O.F. Vila
, N. Rubio
, J. Blanco

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Human mesenchymal stromal cells, whether from the bone marrow or adipose tissue (hASCs), are promising cell therapy agents. However, generation of abundant cells for therapy remains to be a challenge, due to the need of lengthy expansion and the risk of accumulating genomic defects during the process. We show that hASCs can be easily induced to a reversible fast-proliferating phenotype (FP-ASCs) that allows rapid generation of a clinically useful quantity of cells in

Translated title of the contribution	Fast-Proliferating Adipose Tissue Mesenchymal-Stromal-Like Cells for Therapy
Original language	Undefined/Unknown
Pages (from-to)	2908-2920
Number of pages	13
Journal	Stem Cells and Development
Volume	23
Issue number	23
Publication status	Published - 2014

Cite this

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abstract = "Human mesenchymal stromal cells, whether from the bone marrow or adipose tissue (hASCs), are promising cell therapy agents. However, generation of abundant cells for therapy remains to be a challenge, due to the need of lengthy expansion and the risk of accumulating genomic defects during the process. We show that hASCs can be easily induced to a reversible fast-proliferating phenotype (FP-ASCs) that allows rapid generation of a clinically useful quantity of cells in",

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T1 - Fast-Proliferating Adipose Tissue Mesenchymal-Stromal-Like Cells for Therapy

AU - Aguilar, E.

AU - Rodriguez Bago, J.

AU - Soler-Botija, C.

AU - Alieva, M.

AU - Rigola, M.A.

AU - Fuster, C.

AU - Vila, O.F.

AU - Rubio, N.

AU - Blanco, J.

N1 - J EC 1 2014

PY - 2014

Y1 - 2014

N2 - Human mesenchymal stromal cells, whether from the bone marrow or adipose tissue (hASCs), are promising cell therapy agents. However, generation of abundant cells for therapy remains to be a challenge, due to the need of lengthy expansion and the risk of accumulating genomic defects during the process. We show that hASCs can be easily induced to a reversible fast-proliferating phenotype (FP-ASCs) that allows rapid generation of a clinically useful quantity of cells in

AB - Human mesenchymal stromal cells, whether from the bone marrow or adipose tissue (hASCs), are promising cell therapy agents. However, generation of abundant cells for therapy remains to be a challenge, due to the need of lengthy expansion and the risk of accumulating genomic defects during the process. We show that hASCs can be easily induced to a reversible fast-proliferating phenotype (FP-ASCs) that allows rapid generation of a clinically useful quantity of cells in

M3 - Article

SN - 1547-3287

VL - 23

SP - 2908

EP - 2920

JO - Stem Cells and Development

JF - Stem Cells and Development

IS - 23

ER -

Fast-Proliferating Adipose Tissue Mesenchymal-Stromal-Like Cells for Therapy

Abstract

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