Abstract
When dosing renally excreted drugs in patients with kidney disease, it is important to have a reliable estimate of renal function. The estimated glomerular filtration rate (eGFR) is often used in the clinic, although this measure can be inaccurate in certain situations. Choosing the appropriate drug and dosage should therefore not be solely based on the eGFR. In this review, we discuss the physiology behind renal function estimation and drug dosing and propose a step by step approach to dosing renally excreted drugs in patients with kidney disease.
| Translated title of the contribution | Pharmacotherapy in patients with loss of renal function |
|---|---|
| Original language | Dutch |
| Article number | D5089 |
| Journal | Nederlands Tijdschrift voor Geneeskunde |
| Volume | 165 |
| Issue number | 1 |
| Publication status | Published - 17 Dec 2020 |